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耳垂瘢痕疙瘩手术切除与高剂量率近距离放射治疗的结果

Outcomes of Surgical Excision and High-Dose-Rate Brachytherapy for Earlobe Keloids.

作者信息

Fuenmayor Pedro, Quiñonez Hector, Salas Reinaldo, Pujadas Zoe

机构信息

Plastic and Reconstructive Surgery Department, Hospital Universitario de Caracas, Universidad Central de Venezuela, Los Chaguaramos, Distrito Capital, Venezuela.

出版信息

World J Plast Surg. 2021 Jan;10(1):78-84. doi: 10.29252/wjps.10.1.78.

Abstract

BACKGROUND

Radiotherapy as an adjuvant therapy to surgical resection has shown variable rates of recurrence treating earlobe keloids. The purpose of this study was to describe our experience with surgical excision followed by high-dose-rate brachytherapy and present our outcomes after 24 months of follow-up.

METHODS

Retrospective chart of 14 patients with 14 earlobe keloids treated with surgical excision followed by high-dose-rate brachytherapy, between January 2015 and May 2016 were enrolled. Database included demographics, Fitzpatrick skin type, laterality, lesion size, and follow-up visits information. Outcomes were assessed in terms of keloid recurrence rates, complications, and patient subjective aesthetical result satisfaction after 24 months of follow-up.

RESULTS

All procedures were completed without complications. Three patients experienced keloid recurrence after 6 (14.28%) and 12 months (7.14%). Three patients experienced mild signs of self-limited post-radiation dermatitis. Self-assessment of aesthetical result was considered "very good" in 71.43% of patients.

CONCLUSION

Surgical excision followed by high-dose-rate brachytherapy is secure and effective to treat earlobe keloids, and can be considered a first line combined treatment. Larger clinical trials comparing different irradiation protocols are still needed.

摘要

背景

作为手术切除辅助疗法的放射治疗在治疗耳垂瘢痕疙瘩方面显示出不同的复发率。本研究的目的是描述我们采用手术切除加近距离高剂量率放疗的经验,并展示我们24个月随访后的结果。

方法

纳入2015年1月至2016年5月期间14例接受手术切除加近距离高剂量率放疗的耳垂瘢痕疙瘩患者的回顾性病历。数据库包括人口统计学、菲茨帕特里克皮肤分型、病变部位、病变大小及随访信息。随访24个月后,根据瘢痕疙瘩复发率、并发症及患者主观美学结果满意度对疗效进行评估。

结果

所有手术均顺利完成,无并发症发生。3例患者分别在术后6个月(14.28%)和12个月(7.14%)出现瘢痕疙瘩复发。3例患者出现轻度自限性放射性皮炎症状。71.43%的患者对美学结果的自我评估为“非常好”。

结论

手术切除加近距离高剂量率放疗治疗耳垂瘢痕疙瘩安全有效,可被视为一线联合治疗方法。仍需开展更大规模的临床试验以比较不同的放疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab05/8016371/980e60ba9a6e/wjps-10-078-g001.jpg

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Surgical excision and postoperative radiotherapy for keloids.瘢痕疙瘩的手术切除及术后放疗
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