Liagre Arnaud, Martini Francesco, Anduze Yves, Boudrie Hubert, Van Haverbeke Olivier, Valabrega Stefano, Kassir Radwan, Debs Tarek, Petrucciani Niccolò
Bariatric Surgery Unit, Clinique des Cedres, Ramsay Générale de Santé, Cornebarrieu, France.
Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St Andrea Hospital, Sapienza University, Via di Grottarossa 1035-9, 00189, Rome, Italy.
Obes Surg. 2021 Jun;31(6):2691-2700. doi: 10.1007/s11695-021-05323-y. Epub 2021 Apr 9.
The need for revisional procedures after sleeve gastrectomy (SG) for insufficient weight loss or weight regain, gastroesophageal reflux, or other complications is reported to be 18-36% in studies with 10-year follow-up. Single-anastomosis duodeno-ileal bypass (SADI) may be performed as a revisional procedure after SG. This study aims to evaluate the short- and mid-term outcomes of SADI after SG in a referral center for bariatric surgery.
Data of patients who underwent SADI between March 2015 and March 2020 were collected prospectively and analyzed retrospectively. Follow-up comprised clinical and biochemical assessment at 1, 3, 6, 12, 18, and 24 months postoperatively, and once a year thereafter.
Overall, 106 patients underwent SADI after a previous SG. The timeframe between SG and SADI was 50 ± 31.3 months. Postoperative mortality was observed in two cases (1.8%) and morbidity in 15.1% of patients. At 24 months, %total weight loss was 37.6 ± 12.3 and %excess weight loss 76.9 ± 25.2 (64 patients). Three patients were treated for malnutrition during follow-up, two with medical treatment and one with SADI reversal.
SADI after SG provides effective weight loss results in the short-term, even if in the present series the postoperative complication rate was non-negligible. Further trials are needed to establish the more advantageous revisional bariatric procedure after failed SG.
在随访10年的研究中,据报道,因减重不足、体重反弹、胃食管反流或其他并发症而需要在袖状胃切除术(SG)后进行修正手术的比例为18%-36%。单吻合口十二指肠-回肠旁路术(SADI)可作为SG后的修正手术。本研究旨在评估在一家肥胖症手术转诊中心进行SG后SADI的短期和中期结果。
前瞻性收集2015年3月至2020年3月期间接受SADI手术的患者数据,并进行回顾性分析。随访包括术后1、3、6、12、18和24个月以及此后每年一次的临床和生化评估。
总体而言,106例患者在先前接受SG手术后接受了SADI手术。SG与SADI之间的时间间隔为50±31.3个月。观察到2例(1.8%)患者术后死亡,15.1%的患者出现并发症。在24个月时,64例患者的总体重减轻百分比为37.6±12.3,超重减轻百分比为76.9±25.2。3例患者在随访期间接受了营养不良治疗,2例接受药物治疗,1例接受SADI逆转手术。
SG后行SADI在短期内可有效减轻体重,即使在本系列研究中术后并发症发生率也不可忽视。需要进一步试验以确定SG失败后更具优势的肥胖症修正手术。