Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Kobe, Japan.
Adv Exp Med Biol. 2021;1310:449-473. doi: 10.1007/978-981-33-6064-8_16.
Semiconductor nanocrystals (SNCs) are a nano-sized inorganic material. Due to the quantum confinement effect, these crystals exhibit unique optical and electrical properties. This chapter focuses on biological applications of SNCs, ranging from in vitro single-molecule tracking to in vivo fluorescence imaging. The following fundamental properties and technical procedures related to SNCs are also described: structures of SNCs, synthetic procedures and shape control of SNCs, preparation methods of water-soluble SNCs, and conjugation methods of biomolecules.
半导体纳米晶体(SNC)是一种纳米级无机材料。由于量子限域效应,这些晶体表现出独特的光学和电学性质。本章重点介绍 SNC 的生物应用,从体外单分子跟踪到体内荧光成像。还描述了与 SNC 相关的以下基本性质和技术程序:SNC 的结构、SNC 的合成程序和形状控制、水溶性 SNC 的制备方法以及生物分子的连接方法。