Tanaka Shinya, Yamashita Masashi, Saito Hiroshi, Kamiya Kentaro, Maeda Daichi, Konishi Masaaki, Matsue Yuya
Department of Rehabilitation, Nagoya University Hospital, Aichi, Japan.
Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, Kanagawa, Japan.
Curr Heart Fail Rep. 2021 Jun;18(3):107-120. doi: 10.1007/s11897-021-00513-2. Epub 2021 Apr 9.
With a worldwide aging population, frailty and heart failure (HF) have become issues that need to be addressed urgently in cardiovascular clinical practice. In this review, we outline the clinical implications of frailty in HF patients and the potential therapeutic strategies to improve the clinical outcomes of frail patients with HF.
Frailty has physical, psychological, and social domains, each of which is a prognostic determinant for patients with HF, and each domain overlaps with the other, although there are no standardized criteria for diagnosing frailty. Frailty can be targeted for treatment with various interventions, and recent studies have suggested that multidisciplinary intervention could be a promising option for frail patients with HF. However, currently, there is limited data, and further research is needed before its clinical implementation. Frailty and HF share a common background and are strongly associated with each other. More comprehensive assessment and therapeutic interventions for frailty need to be developed to further improve the prognosis and quality of life of frail patients with HF.
随着全球人口老龄化，衰弱和心力衰竭（HF）已成为心血管临床实践中亟待解决的问题。在本综述中，我们概述了衰弱在HF患者中的临床意义以及改善衰弱HF患者临床结局的潜在治疗策略。
衰弱具有身体、心理和社会领域，尽管尚无诊断衰弱的标准化标准，但每个领域都是HF患者的预后决定因素，且各领域相互重叠。衰弱可通过各种干预措施进行针对性治疗，最近的研究表明，多学科干预可能是衰弱HF患者的一个有前景的选择。然而，目前数据有限，在临床应用之前还需要进一步研究。衰弱和HF有共同的背景，且彼此密切相关。需要开展更全面的衰弱评估和治疗干预措施，以进一步改善衰弱HF患者的预后和生活质量。
