3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Barco, Guimarães, Portugal.
ICVS/3B's-PT Government Associate Laboratory, Braga, Guimarães, Portugal.
Biomacromolecules. 2021 May 10;22(5):1815-1834. doi: 10.1021/acs.biomac.1c00013. Epub 2021 Apr 9.
Marine biodiversity is expressed through the huge variety of vertebrate and invertebrate species inhabiting intertidal to deep-sea environments. The extraordinary variety of "forms and functions" exhibited by marine animals suggests they are a promising source of bioactive molecules and provides potential inspiration for different biomimetic approaches. This diversity is familiar to biologists and has led to intensive investigation of metabolites, polysaccharides, and other compounds. However, marine collagens are less well-known. This review will provide detailed insight into the diversity of collagens present in marine species in terms of their genetics, structure, properties, and physiology. In the last part of the review the focus will be on the most common marine collagen sources and on the latest advances in the development of innovative materials exploiting, or inspired by, marine collagens.
海洋生物多样性通过栖息在潮间带到深海环境中的大量脊椎动物和无脊椎动物物种来体现。海洋动物所表现出的“形式和功能”的非凡多样性表明它们是生物活性分子的有前途的来源，并为不同的仿生方法提供了潜在的灵感。这种多样性为生物学家所熟知，并促使他们对代谢物、多糖和其他化合物进行了深入研究。然而，海洋胶原蛋白的知名度较低。本综述将详细介绍海洋物种中存在的胶原蛋白的多样性，包括其遗传学、结构、特性和生理学。在综述的最后一部分，将重点介绍最常见的海洋胶原蛋白来源，以及利用或受海洋胶原蛋白启发开发创新材料的最新进展。
