Department of Preventive Gerontology, Center for Gerontology and Social Science, 221156National Center for Geriatrics and Gerontology, Japan.
J Geriatr Psychiatry Neurol. 2022 May;35(3):392-399. doi: 10.1177/08919887211006468. Epub 2021 Apr 12.
This study aimed to develop a questionnaire for evaluating total sedentary time (ST) and ST with cognitive activity, and to examine the association between ST and cognitive function among Japanese older adults. The questionnaire to evaluate ST comprised 12 items regarding behavior in specific settings, including 8 items on ST with cognitive activity, in a usual week. Older adults aged ≥75 years who participated in a health check-up assessing cognitive function completed the developed questionnaire and subsequently wore an accelerometer and recorded a diary of ST with cognitive activity for a week as validity measures. Cognitive function was assessed with neuropsychological tests covering 4 domains: memory, attention, executive function, and processing speed. Fifty-two participants were included in the validity analysis. Spearman's correlation coefficient indicated fair-to-good agreement between the questionnaire-measured and the diary-measured time for ST with cognitive activity (r = 0.59, p < 0.001), but this was not the case for total ST. Bland-Altman plots showed that the questionnaire-measured total ST contained proportional bias (r = 0.51, p < 0.001). Multiple regression analysis (n = 49) showed longer questionnaire-measured ST with cognitive activity was significantly associated with better neuropsychological test scores (attention: β = -0.38, p = 0.025; executive function: β = -0.46, p = 0.003; and processing speed: β = 0.31, p = 0.041), while total ST was not associated with better cognitive performance. The developed questionnaire showed acceptable validity to measure ST with cognitive activity, which was found to be protectively associated with cognitive function.
本研究旨在开发一种评估总 sedentary time (ST) 和认知活动 ST 的问卷，并探讨日本老年人 ST 与认知功能之间的关系。评估 ST 的问卷包括 12 项关于特定环境下行为的项目，其中 8 项涉及认知活动 ST，在一周内完成。参加健康检查评估认知功能的年龄≥75 岁的老年人完成了开发的问卷，随后佩戴加速度计并记录一周的认知活动 ST 日记作为有效性测量。认知功能通过涵盖 4 个领域的神经心理学测试进行评估：记忆、注意力、执行功能和处理速度。52 名参与者被纳入有效性分析。Spearman 相关系数表明，问卷测量的和日记测量的认知活动 ST 时间之间存在良好到极好的一致性（r = 0.59，p < 0.001），但总 ST 则不然。Bland-Altman 图显示，问卷测量的总 ST 存在比例偏差（r = 0.51，p < 0.001）。多元回归分析（n = 49）表明，问卷测量的认知活动 ST 时间较长与神经心理学测试得分更好显著相关（注意力：β = -0.38，p = 0.025；执行功能：β = -0.46，p = 0.003；处理速度：β = 0.31，p = 0.041），而总 ST 与认知表现的改善无关。开发的问卷在测量认知活动 ST 方面具有可接受的有效性，与认知功能呈保护相关。
