Lu Wensheng, Chu Haifeng, Zheng Xiaodong
Department of Dermatology, Anhui Provincial Hospital Affiliated to Anhui Medical University Hefei, China.
Department of Dermatology, The First Affiliated Hospital of USTC 17th Lujiang Road, Hefei, Anhui, China.
Am J Transl Res. 2021 Mar 15;13(3):1636-1642. eCollection 2021.
Keloids are defined as raised scar tissue that grows excessively and invasively beyond the original wound borders during abnormal, fibroproliferative wound healing. The effects of these lesions on quality of life (QoL) and psychosocial wellbeing have not been assessed in keloid-endemic environments such as China. The purpose of our study was to investigate the QoL and mental health status of patients with keloids in China. The Dermatology Life Quality Index (DLQI) questionnaire and the Symptom Checklist-90 (SCL-90) were used to explore the effects of keloids on patients' QoL and psychosocial wellbeing. The main scoring elements of the DLQI focused on psychological feelings, QoL, and social activities. In addition, the results of the SCL-90 revealed that scores pertaining to interpersonal relationship sensitivity, depression, and anxiety were higher in the visible scar group than in either the invisible scar group or the normal group ( < 0.05). The depression and anxiety scores in the invisible scar group were higher than those in the normal group ( < 0.05), but there were no statistically significant differences in other indices between the invisible scar group and the normal group ( < 0.05). The mental health of female patients was affected to a greater extent than in male patients ( < 0.05). Our findings suggest that psychological and clinical interventions would be beneficial for patients with keloids to improve their QoL.
瘢痕疙瘩被定义为在异常的纤维增生性伤口愈合过程中，超出原始伤口边界过度且侵入性生长的隆起瘢痕组织。在中国等瘢痕疙瘩流行地区，这些病变对生活质量（QoL）和心理社会福祉的影响尚未得到评估。我们研究的目的是调查中国瘢痕疙瘩患者的生活质量和心理健康状况。使用皮肤病生活质量指数（DLQI）问卷和症状自评量表90（SCL - 90）来探究瘢痕疙瘩对患者生活质量和心理社会福祉的影响。DLQI的主要评分要素集中在心理感受、生活质量和社会活动方面。此外，SCL - 90的结果显示，可见瘢痕组在人际关系敏感、抑郁和焦虑方面的得分高于不可见瘢痕组和正常组（<0.05）。不可见瘢痕组的抑郁和焦虑得分高于正常组（<0.05），但不可见瘢痕组与正常组在其他指标上无统计学显著差异（<0.05）。女性患者的心理健康比男性患者受到的影响更大（<0.05）。我们的研究结果表明，心理和临床干预对瘢痕疙瘩患者改善生活质量有益。
