Cai Yujiao, Ye Yujie, Wang Ziyan, Che Dehui, Zhu Bangzhong, Liu Yan, Cao Dongsheng
Department of Plastic and Reconstructive, The Second Affiliated Hospital of Anhui Medical University, Furong Road 678#, Shushan Dist., Hefei, 238000, People's Republic of China.
Department of Burn and Plastic Surgery, Lu'an People's Hospital of Anhui Province, Luan, China.
Aesthetic Plast Surg. 2025 Aug 11. doi: 10.1007/s00266-025-05102-5.
Little is known about the impact of chronic comorbidities on the onset and progression of keloid. The association between keloid and metabolic syndrome has not been investigated in observational controlled studies.
To evaluate the association of keloid with obesity and hypertension using a population-based study.
Information was collected on 151 patients with keloids, anywhere on the body, who visited the Plastic Surgery Department of the Second Affiliated Hospital of Anhui Medical University, and 164 control participants. The patient and control groups had similar mean ages.
The mean ages of the patients and controls were 34.74 ± 16.25 years, and 35.50 ± 12.45 years, respectively. In the univariate analysis and multivariate analyses, body mass index ≥ 25 kg/m (OR = 1.546; p = 0.077) and systolic hypertension (OR = 3.859; p = 0.024) were related to keloid. The two risk factors were independent.
Keloid was associated with overweight and systolic hypertension.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
关于慢性合并症对瘢痕疙瘩发病和进展的影响，人们了解甚少。瘢痕疙瘩与代谢综合征之间的关联尚未在观察性对照研究中进行调查。
采用基于人群的研究评估瘢痕疙瘩与肥胖症和高血压之间的关联。
收集了安徽医科大学第二附属医院整形外科接诊的151例身体任何部位患有瘢痕疙瘩的患者以及164例对照参与者的信息。患者组和对照组的平均年龄相近。
患者组和对照组的平均年龄分别为34.74±16.25岁和35.50±12.45岁。在单因素分析和多因素分析中，体重指数≥25kg/m（比值比=1.546；P=0.077）和收缩期高血压（比值比=3.859；P=0.024）与瘢痕疙瘩有关。这两个危险因素相互独立。
瘢痕疙瘩与超重和收缩期高血压有关。
证据级别III：本刊要求作者为每篇文章指定一个证据级别。有关这些循证医学评级的完整描述，请参阅目录或在线作者须知www.springer.com/00266 。
