Sitaniya Sakshi, Subramani Dharshini, Jadhav Avinash, Sharma Yugal K, Deora Mahendra S, Gupta Aayush
Department of Dermatology, Dr. D.Y. Patil Medical College, Hospital and research centre, Dr. D.Y. Patil University, Pimpri, Pune, Maharashtra, India.
Wound Repair Regen. 2022 May;30(3):409-416. doi: 10.1111/wrr.13015. Epub 2022 Apr 15.
Although the impairment of quality of life (QoL) in individuals with keloids is profound, it has neither been well quantified nor correlated with severity in people with skin of colour. This cross-sectional, questionnaire-based study comprised 110 patients with keloid(s). A physician measured the severity of keloids using the Vancouver Scar scale and impairment of QoL using the patient-filled Hindi version of Dermatology Life Quality Index questionnaire. The relationship among QoL and severity score as well as with components of demographic data was analysed using SPSS. Our study found the severity of keloid(s) to be moderately but significantly correlated with the QoL of its sufferers. Individuals with multiple keloids were found to be significantly younger than those with solitary ones. Itching, pain, along with restricted mobility significantly impacted the QoL as well as severity of keloids. Individuals who had undergone prior treatment were found to have a worse QoL than the treatment naive. Recurrence was found to be associated with lower scar severity, multiple keloids, and younger age. Increasing age, though associated with greater scar severity, lacked any relationship with the QoL. Our study also found that individuals with bigger keloids sought treatment earlier and more often. Hyperpigmented keloid(s), more common in individuals with skin of colour, were associated with a significantly worse QoL and a higher scar severity.
尽管瘢痕疙瘩患者的生活质量（QoL）受损严重，但在有色人种中，其受损程度既未得到充分量化，也未与瘢痕严重程度相关联。这项基于问卷调查的横断面研究纳入了110例瘢痕疙瘩患者。一名医生使用温哥华瘢痕量表测量瘢痕疙瘩的严重程度，使用患者填写的印地语版皮肤病生活质量指数问卷测量生活质量受损情况。使用SPSS分析生活质量与严重程度评分以及人口统计学数据各组成部分之间的关系。我们的研究发现，瘢痕疙瘩的严重程度与其患者的生活质量呈中度但显著的相关性。发现患有多个瘢痕疙瘩的个体比患有单个瘢痕疙瘩的个体明显年轻。瘙痒、疼痛以及活动受限对瘢痕疙瘩的生活质量和严重程度均有显著影响。发现曾接受过治疗的个体的生活质量比未接受过治疗的个体更差。发现复发与较低的瘢痕严重程度、多个瘢痕疙瘩以及较年轻的年龄相关。年龄增长虽与更严重的瘢痕相关，但与生活质量无关。我们的研究还发现，瘢痕疙瘩较大的个体更早且更频繁地寻求治疗。色素沉着性瘢痕疙瘩在有色人种中更为常见，与明显更差的生活质量和更高的瘢痕严重程度相关。
