病例报告：新辅助化疗后保乳手术的3D打印手术导板
Case Report: A 3D-Printed Surgical Guide for Breast-Conserving Surgery After Neoadjuvant Chemotherapy.
作者信息
Wu Zhen-Yu, Kim Guk Bae, Lee Sangwook, Choi Seung Hyun, Kim Namkug, Ko BeomSeok
机构信息
Department of Breast Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Division of Breast Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
出版信息
Front Oncol. 2021 Mar 25;11:633302. doi: 10.3389/fonc.2021.633302. eCollection 2021.
BACKGROUND
A challenging problem for patients undergoing breast-conserving surgery after neoadjuvant chemotherapy (NACT) is the accuracy of preoperative tumor localization. After chemotherapy, the original tumor is likely to shrink or scatter dramatically or even show complete remission. For breast-conserving surgery, the development of a guidance device to accurately estimate the resection area is imperative.
CASE PRESENTATION
We produced a three-dimensional (3D)-printed breast surgical guide (BSG) based on prone and supine magnetic resonance imaging (MRI). This device was tested on a patient who underwent breast-conserving surgery after NACT. Both ultrasonography and MRI revealed that the tumor shrank substantially after NACT. Identifying the target tumor area using pre-NACT MRI was feasible, and the tumor was safely removed with clear resection margins.
CONCLUSION
The BSG has several advantages over conventional methods for tumor localization after NACT. In particular, the BSG provided precise quantitative MRI information about the tumor area.
背景
对于接受新辅助化疗（NACT）后行保乳手术的患者而言，术前肿瘤定位的准确性是一个具有挑战性的问题。化疗后，原发肿瘤可能会显著缩小或分散，甚至出现完全缓解。对于保乳手术来说，开发一种能够准确估计切除范围的引导装置势在必行。
病例介绍
我们基于俯卧位和仰卧位磁共振成像（MRI）制作了一种三维（3D）打印的乳腺手术引导器（BSG）。该装置在一名接受NACT后行保乳手术的患者身上进行了测试。超声检查和MRI均显示，NACT后肿瘤明显缩小。使用NACT前的MRI识别目标肿瘤区域是可行的，肿瘤被安全切除，切缘清晰。
结论
与NACT后肿瘤定位的传统方法相比，BSG具有多个优势。特别是，BSG提供了有关肿瘤区域的精确MRI定量信息。
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