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先进的个性化结核病诊断策略:当前技术与临床方法

Strategies for advanced personalized tuberculosis diagnosis: Current technologies and clinical approaches.

作者信息

Chen Xuerong, Hu Tony Y

机构信息

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.

Center for Cellular and Molecular Diagnostics, School of Medicine, Tulane University, New Orleans, LA 70112, USA.

出版信息

Precis Clin Med. 2021 Jan 18;4(1):35-44. doi: 10.1093/pcmedi/pbaa041. eCollection 2021 Mar.

DOI:10.1093/pcmedi/pbaa041
PMID:33842836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8023014/
Abstract

Diagnosis of tuberculosis can be difficult as advances in molecular diagnosis approaches (especially nanoparticles combined with high-throughput mass spectrometry for detecting mycobacteria peptide) and personalized medicine result in many changes to the diagnostic framework. This review will address issues concerning novel technologies from bench to bed and new strategies for personalized tuberculosis diagnosis.

摘要

由于分子诊断方法(特别是纳米颗粒与用于检测分枝杆菌肽的高通量质谱联用)和个性化医疗的进展给诊断框架带来了诸多变化,结核病的诊断可能会变得困难。本综述将探讨从实验室到临床的新技术问题以及个性化结核病诊断的新策略。

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WHO global progress report on tuberculosis elimination.世界卫生组织结核病消除全球进展报告。
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Detection of Tuberculosis Recurrence, Diagnosis and Treatment Response by a Blood Transcriptomic Risk Signature in HIV-Infected Persons on Antiretroviral Therapy.通过血液转录组风险特征检测接受抗逆转录病毒治疗的HIV感染者的结核病复发、诊断及治疗反应
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进食后胸骨后疼痛患者的诊治:病例报告
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