Chen Xuerong, Hu Tony Y
Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Center for Cellular and Molecular Diagnostics, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Precis Clin Med. 2021 Jan 18;4(1):35-44. doi: 10.1093/pcmedi/pbaa041. eCollection 2021 Mar.
Diagnosis of tuberculosis can be difficult as advances in molecular diagnosis approaches (especially nanoparticles combined with high-throughput mass spectrometry for detecting mycobacteria peptide) and personalized medicine result in many changes to the diagnostic framework. This review will address issues concerning novel technologies from bench to bed and new strategies for personalized tuberculosis diagnosis.
由于分子诊断方法(特别是纳米颗粒与用于检测分枝杆菌肽的高通量质谱联用)和个性化医疗的进展给诊断框架带来了诸多变化,结核病的诊断可能会变得困难。本综述将探讨从实验室到临床的新技术问题以及个性化结核病诊断的新策略。