J Clin Rheumatol. 2022 Mar 1;28(2):e545-e551. doi: 10.1097/RHU.0000000000001740.
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic disease with marked clinical and radiological heterogeneity. It is characterized by a combination of dermatological and osteoarticular manifestations. The treatment of SAPHO syndrome is not yet codified. It includes several therapeutic options such as anti-inflammatory drugs, bisphosphonates, antibiotics, conventional disease-modifying antirheumatic drugs, and biological treatment.This article aims to provide an updated review of the different pharmacological options for SAPHO syndrome. We also propose a therapeutic algorithm for the management of this disease.
滑膜炎-痤疮-脓疱病-骨肥厚-骨炎（SAPHO）综合征是一种罕见的慢性疾病，具有明显的临床和影像学异质性。其特征是皮肤和骨关节表现的组合。SAPHO 综合征的治疗尚未规范化。它包括几种治疗选择，如抗炎药、双膦酸盐、抗生素、传统的疾病修饰抗风湿药物和生物治疗。本文旨在提供 SAPHO 综合征不同药物治疗选择的最新综述。我们还提出了这种疾病治疗的治疗算法。
