Melnik Bodo C, Schmitz Gerd, John Swen Malte
Abteilung Dermatologie, Umweltmedizin und Gesundheitstheorie, Universität Osnabrück, Am Finkenhügel 7a, 49076, Osnabrück, Deutschland.
Institut für Klinische Chemie und Laboratoriumsmedizin, Universitätsklinik Regensburg, Regensburg, Deutschland.
MMW Fortschr Med. 2021 Apr;163(Suppl 4):3-9. doi: 10.1007/s15006-021-9652-x.
Recent epidemiological studies associate the consumption of non-fermented cow's milk, but not fermented milk products, with an increased risk of diseases of civilization.
Presentation of epidemiological and pathophysiological data on health risks associated with milk consumption.
Selective PubMed surveys between 2005-2020 considering epidemiological studies which clearly differentiate between non-fermented versus fermented milk and its potential health risks.
Epidemiological studies confirm a correlation between milk consumption and birthweight, linear growth during puberty, acne vulgaris, type 2 diabetes mellitus, prostate cancer, breast cancer, hepatocellular carcinoma, non-Hodgkin lymphoma, Parkinson's disease and over-all mortality. In comparison to milk consumption, the intake of fermented milk/milk products exhibits neutral to beneficial health effects, which are explained by attenuated mTORC1 signaling due to bacterial fermentation of milk.
Long-term persistent consumption of non-fermented milk, but not fermented milk/milk products, might increase the risk of diseases of civilization. The avoidance of milk, especially pasteurized fresh milk, may enhance the prevention and reduce the recurrence of common Western diseases of civilization.
近期的流行病学研究表明，饮用未发酵的牛奶而非发酵乳制品会增加患文明病的风险。
介绍与饮用牛奶相关的健康风险的流行病学和病理生理学数据。
对2005年至2020年间的PubMed进行选择性检索，纳入明确区分未发酵牛奶与发酵牛奶及其潜在健康风险的流行病学研究。
流行病学研究证实，饮用牛奶与出生体重、青春期线性生长、寻常痤疮、2型糖尿病、前列腺癌、乳腺癌、肝细胞癌、非霍奇金淋巴瘤、帕金森病及总体死亡率之间存在关联。与饮用牛奶相比，摄入发酵牛奶/奶制品对健康呈现中性至有益影响，这可归因于牛奶经细菌发酵后mTORC1信号减弱。
长期持续饮用未发酵牛奶而非发酵牛奶/奶制品可能会增加患文明病的风险。避免饮用牛奶，尤其是巴氏杀菌鲜牛奶，可能会增强对常见西方文明病的预防并减少其复发。
