Department of Ultrasound, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, 251 Yaojiayuan Road, Beijing, 100026, China.
Department of Ultrasound, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
BMC Pregnancy Childbirth. 2021 Apr 12;21(1):296. doi: 10.1186/s12884-021-03743-3.
Necrotising funisitis (NF) is a rare, chronic stage of funisitis, a severe inflammation of the umbilical cord and an important risk factor for fetal adverse outcomes. NF is characterized by yellow-white bands running parallel to the umbilical blood vessels. These bands consist of inflammatory cells, necrotic debris, and calcium deposits. Calcification is visible in ultrasonography, which makes it possible to suspect NF when umbilical vascular wall calcification is detected by prenatal ultrasonography.
Ultrasonography revealed calcification of the umbilical venous wall in an expectant 31-year-old woman who was gravida 1, para 0. The woman required emergency cesarean section because of fetal distress and suspected umbilical cord torsion at 31 weeks gestation. The root of the umbilical cord was quite fragile and broke during the operation. The pathological results on the placenta showed histologic chorioamnionitis and NF. The infant was diagnosed to have neonatal sepsis and acidosis after delivery but was discharged without severe complications after a one-month hospitalization that included antibiotic and supportive therapy.
NF is a rare and severe inflammation of the umbilical cord. Umbilical vascular wall calcification discovered in prenatal ultrasonography is diagnostically helpful.
坏死性脐炎（NF）是一种罕见的慢性脐炎阶段，是脐带严重炎症的一个重要胎儿不良结局的危险因素。NF 的特征是与脐血管平行的黄白色带。这些带由炎症细胞、坏死碎片和钙沉积组成。在超声检查中可见钙化，因此当产前超声检查发现脐血管壁钙化时，就可以怀疑 NF。
超声检查显示一名 31 岁的初产妇 1 孕 0，其脐静脉壁有钙化。由于胎儿窘迫和疑似脐带扭转，这名妇女在 31 周妊娠时需要紧急剖宫产。脐带根部非常脆弱，在手术过程中破裂。胎盘的病理结果显示组织学绒毛膜羊膜炎和 NF。婴儿出生后被诊断为新生儿败血症和酸中毒，但经过一个月的住院治疗，包括抗生素和支持治疗后，没有严重并发症出院。
NF 是一种罕见且严重的脐带炎症。产前超声检查发现的脐血管壁钙化有助于诊断。
