Demeyere Nele, Haupt Marleen, Webb Sam S, Strobel Lea, Milosevich Elise T, Moore Margaret J, Wright Hayley, Finke Kathrin, Duta Mihaela D
Department of Experimental Psychology, University of Oxford, New Radcliffe House, Radcliffe Observatory Quarter, Oxford, OX2 6AE, UK.
Department of General and Experimental Psychology, Ludwig-Maximilians-Universität München, Munich, Germany.
Sci Rep. 2021 Apr 12;11(1):8000. doi: 10.1038/s41598-021-87287-8.
Here, we present the Oxford Cognitive Screen-Plus, a computerised tablet-based screen designed to briefly assess domain-general cognition and provide more fine-grained measures of memory and executive function. The OCS-Plus was designed to sensitively screen for cognitive impairments and provide a differentiation between memory and executive deficits. The OCS-Plus contains 10 subtasks and requires on average 24 min to complete. In this study, 320 neurologically healthy ageing participants (age M = 62.66, SD = 13.75) from three sites completed the OCS-Plus. The convergent validity of this assessment was established in comparison to the ACE-R, CERAD and Rey-Osterrieth. Divergent validity was established through comparison with the BDI and tests measuring divergent cognitive domains. Internal consistency of each subtask was evaluated, and test-retest reliability was determined. We established the normative impairment cut-offs for each of the subtasks. Predicted convergent and divergent validity was found, high internal consistency for most measures was also found with the exception of restricted range tasks, as well as strong test-retest reliability, which provided evidence of test stability. Further research demonstrating the use and validity of the OCS-Plus in various clinical populations is required. The OCS-Plus is presented as a standardised cognitive assessment tool, normed and validated in a sample of neurologically healthy participants. The OCS-Plus will be available as an Android App and provides an automated report of domain-general cognitive impairments in executive attention and memory.
在此，我们介绍牛津认知筛查增强版（Oxford Cognitive Screen-Plus），这是一种基于平板电脑的计算机化筛查工具，旨在简要评估一般领域认知，并提供更精细的记忆和执行功能测量。OCS-Plus旨在灵敏地筛查认知障碍，并区分记忆缺陷和执行功能缺陷。OCS-Plus包含10个分任务，平均需要24分钟完成。在本研究中，来自三个地点的320名神经功能正常的老年参与者（年龄M = 62.66，标准差 = 13.75）完成了OCS-Plus。通过与ACE-R、CERAD和雷-奥斯特里思测验（Rey-Osterrieth）比较，确立了该评估的聚合效度。通过与BDI及测量不同认知领域的测验比较，确立了区分效度。评估了每个分任务的内部一致性，并确定了重测信度。我们确立了每个分任务的标准化损伤临界值。发现了预测的聚合效度和区分效度，除范围受限任务外，大多数测量的内部一致性也很高，同时重测信度很强，这为测验稳定性提供了证据。需要进一步研究以证明OCS-Plus在各种临床人群中的应用和效度。OCS-Plus作为一种标准化认知评估工具推出，在神经功能正常的参与者样本中进行了标准化和效度验证。OCS-Plus将作为一款安卓应用程序提供，并提供执行注意力和记忆方面一般领域认知障碍的自动报告。
