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儿童非典型性肺转移瘤:影像学表现谱。

Atypical pulmonary metastases in children: the spectrum of radiologic findings.

机构信息

Pediatric Radiology Unit, Ruth Rappaport Children's Hospital, 8 HaAliya HaShniya Street, 3109601, Haifa, Israel.

Department of Radiology, Rambam Health Care Campus, Haifa, Israel.

出版信息

Pediatr Radiol. 2021 Sep;51(10):1907-1916. doi: 10.1007/s00247-021-05035-6. Epub 2021 Apr 13.

DOI:10.1007/s00247-021-05035-6
PMID:33847786
Abstract

Pulmonary nodules present a diagnostic challenge when they appear as atypical metastases in pediatric oncology patients. Chest computed tomography (CT) is the primary imaging modality for assessing lung nodules. In pediatric populations, Wilms tumor and osteosarcoma are the cancers most likely to produce pulmonary metastasis, both typical and atypical. This pictorial essay provides a thorough description of the specific radiologic features of atypical pediatric pulmonary metastases, and their pathogenesis and differential diagnosis. We also address diagnostic approaches to incidental lung nodules in healthy children found in the literature. Our aim is to help radiologists identify atypical lung metastases on CT, ensuring that children receive prompt, and potentially lifesaving, treatment.

摘要

当肺部结节在儿科肿瘤患者中表现为非典型转移时,会带来诊断上的挑战。胸部计算机断层扫描(CT)是评估肺部结节的主要影像学手段。在儿科人群中,Wilms 瘤和骨肉瘤是最有可能产生肺部转移的癌症,包括典型和非典型转移。本文通过图像形式全面描述了非典型性儿科肺部转移的特定放射学特征及其发病机制和鉴别诊断。我们还讨论了文献中健康儿童偶然发现肺部结节的诊断方法。我们的目的是帮助放射科医生在 CT 上识别非典型性肺转移,以确保儿童得到及时的、可能挽救生命的治疗。

相似文献

1
Atypical pulmonary metastases in children: the spectrum of radiologic findings.儿童非典型性肺转移瘤:影像学表现谱。
Pediatr Radiol. 2021 Sep;51(10):1907-1916. doi: 10.1007/s00247-021-05035-6. Epub 2021 Apr 13.
2
Atypical pulmonary metastases in children: pictorial review of imaging patterns.儿童非典型性肺转移瘤:影像学表现综述。
Pediatr Radiol. 2021 Jan;51(1):131-139. doi: 10.1007/s00247-020-04821-y. Epub 2020 Sep 23.
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CT-guided hook-wire localization of pulmonary nodules in children prior to atypical resection by thoracoscopy: Practical aspects.胸腔镜非典型切除术前CT引导下小儿肺结节的钩丝定位:实际操作要点
Radiologia (Engl Ed). 2021 Sep-Oct;63(5):415-424. doi: 10.1016/j.rxeng.2021.06.001.
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Do characteristics of pulmonary nodules on computed tomography in children with known osteosarcoma help distinguish whether the nodules are malignant or benign?儿童已知骨肉瘤的 CT 肺部结节特征有助于区分结节的良恶性吗?
J Pediatr Surg. 2011 Apr;46(4):729-735. doi: 10.1016/j.jpedsurg.2010.11.027.
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Chest radiography versus chest CT in the evaluation for pulmonary metastases in patients with Wilms' tumor: a retrospective review.胸部X线摄影与胸部CT在肾母细胞瘤患者肺转移评估中的比较:一项回顾性研究
Pediatr Radiol. 2000 Aug;30(8):533-7; discussion 537-9. doi: 10.1007/s002470000204.
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Minimally invasive thoracoscopic ultrasound for localization of pulmonary nodules in children.微创胸腔镜超声用于儿童肺结节的定位
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Pulmonary nodules discovered during the initial evaluation of pediatric patients with bone and soft-tissue sarcoma.在对患有骨肉瘤和软组织肉瘤的儿科患者进行初始评估期间发现的肺结节。
Pediatr Blood Cancer. 2008 Jun;50(6):1147-53. doi: 10.1002/pbc.21454.
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Radiological nodule behavior: A critical parameter in the surgical management of pediatric pulmonary metastases.放射学结节行为:小儿肺转移瘤外科治疗中的关键参数。
Turk J Pediatr. 2018;60(4):372-379. doi: 10.24953/turkjped.2018.04.003.
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Significance and management of computed tomography detected pulmonary nodules: a report from the National Wilms Tumor Study Group.计算机断层扫描检测到的肺结节的意义及管理:来自国家肾母细胞瘤研究组的报告
Int J Radiat Oncol Biol Phys. 1999 Jun 1;44(3):579-85. doi: 10.1016/s0360-3016(99)00086-3.
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Clinical significance of pulmonary nodules detected on abdominal CT in pediatric patients.小儿腹部CT检查发现肺部结节的临床意义
Pediatr Radiol. 2015 Nov;45(12):1753-60. doi: 10.1007/s00247-015-3407-8. Epub 2015 Jul 12.

引用本文的文献

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Chemotherapy-induced cavitating Wilms' tumor pulmonary metastasis: Active disease or scarring? A case report and literature review.化疗诱导的肾母细胞瘤肺转移空洞形成:活动性疾病还是瘢痕形成?一例病例报告及文献综述
Front Pediatr. 2023 Feb 28;11:1083168. doi: 10.3389/fped.2023.1083168. eCollection 2023.

本文引用的文献

1
Solitary round pulmonary lesions in the pediatric population: a pictorial review.儿科人群中的孤立性圆形肺病变:影像学综述
Acta Radiol Open. 2019 May 31;8(5):2058460119851998. doi: 10.1177/2058460119851998. eCollection 2019 May.
2
Abscess mimicking lung metastasis in a 10-year-old boy - case report.一名10岁男孩中类似肺转移瘤的脓肿——病例报告
Pol J Radiol. 2010 Oct;75(4):55-7.