Department of Medical Laser, Dankook University Graduate School of Medicine, 119, Dandae-ro, Dongnam-gu, Cheonan-si, Chungnam, 31116, South Korea.
Department of Biomedical Laboratory Science, Dankook University College of Health Sciences, 119, Dandae-ro, Dongnam-gu, Cheonan-si, Chungnam, 31116, South Korea.
Environ Sci Pollut Res Int. 2021 Aug;28(32):44332-44338. doi: 10.1007/s11356-021-13852-3. Epub 2021 Apr 13.
Rotavirus A is the most common cause of infectious diarrhea worldwide. This study aimed to retrospectively study and analyze 4009 stool samples that were tested for viruses causing diarrhea, using multiplex reverse transcription PCR at Dankook University Hospital between 2010 and 2019. Furthermore, we determined the correlation between these factors and various climatic factors, including wind-chill temperature, relative humidity, rate of sunshine, and particulate matter. Rotavirus A infections occurred frequently in February, March, and April on an annual basis. Furthermore, during the study, the detection rate was highest at 17.0% (n=61/359) in 2011. Based on an analysis of weather big data, patient age, and period-specific infection during the summer, when the wind-chill temperature and relative humidity were high, the Rotavirus A infection rate was very low. Relative humidity (p=0.020) and particulate matter (p=0.049) were associated with the average number of monthly cases of Rotavirus A infection. However, wind chill temperature (p=0.074) and rate of sunshine (p=0.993) were not associated with the average monthly distribution of Rotavirus A cases. These results indicate that Rotavirus A infection was correlated with relative humidity and particulate matter during the study period and further the current understanding of the distribution of Rotavirus A infections resulting from climatic factors and particulate matter. This could help establish climate-related health policies to reduce the incidence of diarrhea and guide the development of vaccines against Rotavirus A.
轮状病毒 A 是全世界引起感染性腹泻最常见的病原体。本研究旨在回顾性分析 2010 年至 2019 年期间 Dankook 大学医院采用多重逆转录聚合酶链反应检测病毒引起的腹泻的 4009 份粪便样本。此外，我们还确定了这些因素与各种气候因素（风寒温度、相对湿度、日照率和颗粒物）之间的相关性。轮状病毒 A 感染在每年的 2 月、3 月和 4 月频繁发生。此外，在研究期间，2011 年的检出率最高，为 17.0%（n=61/359）。基于对天气大数据、患者年龄和夏季特定时期感染的分析，当风寒温度和相对湿度较高时，轮状病毒 A 的感染率非常低。相对湿度（p=0.020）和颗粒物（p=0.049）与轮状病毒 A 每月感染例数的平均值有关。然而，风寒温度（p=0.074）和日照率（p=0.993）与轮状病毒 A 每月分布无关。这些结果表明，在研究期间，轮状病毒 A 感染与相对湿度和颗粒物有关，进一步了解了气候因素和颗粒物引起的轮状病毒 A 感染的分布情况。这有助于制定与气候相关的卫生政策，以降低腹泻的发病率，并指导针对轮状病毒 A 的疫苗开发。
