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病例报告:一位 COVID-19 患者表现为轻度横纹肌溶解症。

Case Report: A COVID-19 Patient Presenting with Mild Rhabdomyolysis.

机构信息

1Department of Internal Medicine, Medical Faculty, Biruni University, Istanbul, Turkey.

2Department of Pulmonary Diseases, Medical Faculty, Biruni University, Istanbul, Turkey.

出版信息

Am J Trop Med Hyg. 2020 Aug;103(2):847-850. doi: 10.4269/ajtmh.20-0583. Epub 2020 Jun 19.

Abstract

The news was reported from the Wuhan region of China about a novel corona virus in the end of 2019. After spreading around the world, a pandemic was declared by the WHO. Depending on the different involvement of the disease, the most common symptoms are fever, cough, and dyspnea. However, some indeterminate symptoms that make diagnosis difficult, such as myalgia and fatigue, can also be seen alone, without the typical clinical picture. We describe a patient with COVID-19 pneumonia, the only complaint of which is myalgia, and the first diagnosis is mild rhabdomyolysis. The patient had no evidence or history other than viral infection that could explain muscle pain and also increased level of muscle enzymes. When mild rhabdomyolysis lack of myoglobinuria and complications was diagnosed, treatment-related rhabdomyolysis was also avoided as no treatment related to COVID-19 was initiated yet. Apart from the typical symptoms leading to the typical diagnosis of COVID-19 at the first admission, SARS-CoV-2 related with rhabdomyolysis should also be kept in mind.

摘要

2019 年末,中国武汉地区报道了一种新型冠状病毒的消息。该病毒在全球传播后,世界卫生组织宣布了大流行。根据疾病的不同累及情况,最常见的症状是发热、咳嗽和呼吸困难。然而,一些不典型的症状,如肌痛和乏力,也可能单独出现,而没有典型的临床症状。我们描述了一例 COVID-19 肺炎患者,其唯一的主诉是肌痛,最初诊断为轻度横纹肌溶解症。该患者除病毒感染外,没有任何其他证据或病史可以解释肌肉疼痛和肌酶水平升高。当诊断为轻度横纹肌溶解症且无肌红蛋白尿和并发症时,由于尚未开始与 COVID-19 相关的治疗,因此也避免了与治疗相关的横纹肌溶解症。除了首次入院时导致 COVID-19 典型诊断的典型症状外,还应注意与横纹肌溶解症相关的 SARS-CoV-2。

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