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肉毒杆菌毒素在运动障碍治疗中的应用经验

Experiences on The Administration of Botulinum Toxin in Movement Disorders.

作者信息

Tuğan Yıldız Buket, Tuncel Berktaş Deniz

机构信息

Kahramanmaraş Sütçü İmam University, School of Medicine, Department of Neurology, Kahramanmaraş, Turkey.

出版信息

J Transl Int Med. 2021 Jan 5;9(1):52-56. doi: 10.2478/jtim-2021-0003. eCollection 2021 Mar.

Abstract

BACKGROUND AND OBJECTIVES

Botulinum toxin injection has been used for many years for various indications such as cervical dystonia, blepharospasm, oromandibular dystonia, hemifacial spasm in neurology. Botulinum toxin injections have been made in our clinic for about ten years. We want to report our experiences about botulinum toxin treatment in neurologic disease.

METHODS

In this study, the data of the patients receiving BoNT injection between January 2018 and December 2019 was retrospectively analyzed. Age, gender, botulinum toxin indications, and mean dose, duration of efficacy, side effects noted for each injection were recorded.

RESULTS

There were 122 patients who received botulinum toxin injections between January 2018 and December 2019. Of the 122 patients identified, 28 had cervical dystonia, 61 had HFS, 21 had blepharospasm, 4 had generalized dystonia, 1 had hemidystonia following thalamic bleeding, 1 had tardive dystonia, 4 had migraine, 1 had bruxism and 1 had both migraine and bruxism.

CONCLUSION

BoNT injection is a treatment that has been used for various indications in neurology for almost 40 years. Side effects are limited and temporary with appropriate injections. We also had a wide range of indication profiles and high numbers of patients to whom we administered the BoNT treatment.

摘要

背景与目的

肉毒杆菌毒素注射多年来一直用于多种适应症,如神经科的颈部肌张力障碍、眼睑痉挛、口下颌肌张力障碍、偏侧面肌痉挛。在我们诊所进行肉毒杆菌毒素注射已有约十年时间。我们想报告我们在神经疾病肉毒杆菌毒素治疗方面的经验。

方法

在本研究中,对2018年1月至2019年12月期间接受肉毒杆菌毒素注射的患者数据进行回顾性分析。记录年龄、性别、肉毒杆菌毒素适应症、平均剂量、疗效持续时间以及每次注射所记录的副作用。

结果

2018年1月至2019年12月期间有122例患者接受了肉毒杆菌毒素注射。在这122例确诊患者中,28例患有颈部肌张力障碍,61例患有偏侧面肌痉挛,21例患有眼睑痉挛,4例患有全身性肌张力障碍,1例在丘脑出血后患有偏侧肌张力障碍,1例患有迟发性肌张力障碍,4例患有偏头痛,1例患有磨牙症,1例同时患有偏头痛和磨牙症。

结论

肉毒杆菌毒素注射是一种在神经科用于多种适应症近40年的治疗方法。通过适当注射,副作用有限且为暂时性。我们也有广泛的适应症范围以及大量接受肉毒杆菌毒素治疗的患者。

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