Mwamba Jean Jimmy Kalfando, Mukuku Olivier, Kasongo Kumelundu, Tamubango Herman Kitoko, Kibwe Cynthia Mwenya, Tshikala Ignace Nday, Kabue Jeannot Bakajika, Ilunga Jean-Paul Nkenga, Mumbere Philémon Matumo, Iteke Rivain Fefe, Nsambi Joseph Bulanda, Kakudji Prosper Luhete, Kinenkinda Xavier Kalume, Kakoma Jean-Baptiste
Département de Gynécologie Obstétrique, Faculté de Médecine, Université de Lubumbashi, Lubumbashi, République Démocratique du Congo.
Institut Supérieur des Techniques Médicales de Lubumbashi, Lubumbashi, République Démocratique du Congo.
Pan Afr Med J. 2023 Aug 22;45:177. doi: 10.11604/pamj.2023.45.177.36977. eCollection 2023.
in Lubumbashi, as in upscale areas where explorations of fertility are very clever, the spermogram remains the essential analysis in the diagnosis of male infertility. This is the cause of 40% of couple infertility. The spermogram is the first step in identifying seminal abnormalities. The objective of this study was to determine the epidemiological-clinical and seminal profile of the man consulting for the desire to procreate in Lubumbashi.
this was a cross-sectional study. We received 202 subjects in Lubumbashi, whose spermogram was performed from August 1, 2020 to July 31, 2021. The semen parameters were studied and interpreted according to WHO standards (2010) with studies of factors associated with their disturbance. Bivariate and multivariate analyzes had been carried out. The statistical significance threshold was set at p < 0.05.
the epidemiological-clinical profile of the respondents was as follows: the most represented age group was 30 to 39 years; infertility was primary in 80.69% of cases; the duration of the desire for paternity was 2 years at most in 44.55% of cases. The sperm abnormalities found were: oligozoospermia (40.09%), azoospermia (11.38%), asthenozoospermia (18.31%) and teratozoospermia (10.39%). Oligozoospermia was significantly associated with varicocele (ORa = 10.9 [3.0-39.5]; p < 0.0001), genital infection (ORa =2.7 [1.0-7, 2]; p = 0.041) and obesity (ORa = 2.6 [1.0-7.9]; p = 0.020) while azoospermia was the cure for inguinal hernia (ORa = 4.2 [1.0-17.2]; p = 0.049) and malnutrition (ORa =6.0 [1.2-29.7]; p = 0.027). Asthenozoospermia was significantly associated with the age group of 40 to 49 years (ORa = 6.6 [1.2-37.4]; p = 0.034), tobacco (ORa =7.5 [2.7 -21.0]; p = 0.000), undernutrition (ORa = 7.7 [1.0-61.9]; p = 0.045) and overweight (ORa =3.8 [1.3-11, 5]; p=0.019). Teratozoospermia was significantly associated with smoking (ORa = 5.6 [1.8-17.7]; p = 0.003) and overweight (ORa =5.3 [1.2-23.3]; p = 0.027).
more than half of the respondents had, of the three main fertility parameters, at least one that was disturbed. Sperm count was the most affected parameter. Alcohol, tobacco, genital infection and malnutrition were the most common risk factors for the abnormalities observed.
在卢本巴希，如同在生育研究非常精细的高档地区一样，精液分析仍然是男性不育症诊断中的关键检查。这是导致40%夫妻不育的原因。精液分析是识别精液异常的第一步。本研究的目的是确定在卢本巴希因生育意愿前来咨询的男性的流行病学 - 临床及精液特征。
这是一项横断面研究。我们在卢本巴希接收了202名受试者，他们的精液分析在2020年8月1日至2021年7月31日期间进行。根据世界卫生组织（2010年）标准研究精液参数并对其进行解读，同时研究与参数紊乱相关的因素。进行了双变量和多变量分析。统计学显著性阈值设定为p < 0.05。
受访者的流行病学 - 临床特征如下：最具代表性的年龄组为30至39岁；80.69%的病例为原发性不育；44.55%的病例中生育意愿持续时间最长为2年。发现的精液异常情况有：少精子症（40.09%）、无精子症（11.38%）、弱精子症（18.31%）和畸形精子症（10.39%）。少精子症与精索静脉曲张显著相关（优势比a = 10.9 [3.0 - 39.5]；p < 0.0001）、生殖器感染（优势比a = 2.7 [1.0 - 7.2]；p = 0.041）和肥胖（优势比a = 2.6 [1.0 - 7.9]；p = 0.020），而无精子症与腹股沟疝手术史（优势比a = 4.2 [1.0 - 17.2]；p = 0.049）和营养不良（优势比a = 6.0 [1.2 - 29.7]；p = 0.027）有关。弱精子症与40至49岁年龄组显著相关（优势比a = 6.6 [1.2 - 37.4]；p = 0.034）、吸烟（优势比a = 7.5 [2.7 - 21.0]；p = 0.000）、营养不足（优势比a = 7.7 [1.0 - 61.9]；p = 0.045）和超重（优势比a = 3.8 [1.3 - 11.5]；p = 0.019）。畸形精子症与吸烟（优势比a = 5.6 [1.8 - 17.7]；p = 0.003）和超重（优势比a = 5.3 [1.2 - 23.3]；p = 0.027）显著相关。
超过一半的受访者在三个主要生育参数中至少有一个出现紊乱。精子数量是受影响最严重的参数。酒精、烟草、生殖器感染和营养不良是观察到的异常情况最常见的危险因素。
