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通过X射线散射方法对肽纳米管进行多尺度结构解析

Multiscale Structural Elucidation of Peptide Nanotubes by X-Ray Scattering Methods.

作者信息

Narayanan Theyencheri, Rüter Axel, Olsson Ulf

机构信息

ESRF-The European Synchrotron, Grenoble, France.

Division of Physical Chemistry, Lund University, Lund, Sweden.

出版信息

Front Bioeng Biotechnol. 2021 Mar 29;9:654339. doi: 10.3389/fbioe.2021.654339. eCollection 2021.

DOI:10.3389/fbioe.2021.654339
PMID:33855016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8039368/
Abstract

This mini-review presents the structural investigations of the self-assembled peptide nanotubes using X-ray scattering techniques. As compared to electron microscopy, scattering methods enable studies of nanotubes in solution under the appropriate physicochemical conditions and probe their formation mechanism. In addition, a combination of X-ray scattering methods allow the elucidation of structural organization from the molecular scale to the dimension of nanotubes.

摘要

本综述介绍了利用X射线散射技术对自组装肽纳米管进行的结构研究。与电子显微镜相比,散射方法能够在适当的物理化学条件下研究溶液中的纳米管,并探究其形成机制。此外,X射线散射方法的结合能够阐明从分子尺度到纳米管尺寸的结构组织。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2eb/8039368/3077c04c0f1e/fbioe-09-654339-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2eb/8039368/f4a4672d55d3/fbioe-09-654339-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2eb/8039368/3077c04c0f1e/fbioe-09-654339-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2eb/8039368/f4a4672d55d3/fbioe-09-654339-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2eb/8039368/3077c04c0f1e/fbioe-09-654339-g0002.jpg

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Chem Commun (Camb). 2020 Oct 14;56(80):11977-11980. doi: 10.1039/d0cc04299d. Epub 2020 Sep 7.
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A microvolume shear cell for combined rheology and x-ray scattering experiments.
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