Behavioral Pharmacology Research Unit.
Department of Health, Behavior and Society.
Exp Clin Psychopharmacol. 2022 Oct;30(5):575-583. doi: 10.1037/pha0000462. Epub 2021 Apr 15.
Cannabis products available for retail purchase are often marketed based on purported plant species (e.g., "indica" or "sativa"). The cannabis industry frequently claims that indica versus sativa cannabis elicits unique effects and/or is useful for different therapeutic indications. Few studies have evaluated use patterns, beliefs, subjective experiences, and situations in which individuals use indica versus sativa. A convenience sample of cannabis users ( = 179) was surveyed via Amazon Mechanical Turk (mTurk). Participants were asked about their prior use of, subjective experiences with, and opinions on indica versus sativa cannabis and completed hypothetical purchasing tasks for both cannabis subtypes. Participants reported a greater preference to use indica in the evening and sativa in the morning and afternoon. Participants were more likely to perceive feeling "sleepy/tired" or "relaxed" after using indica and "alert," "energized," and "motivated" after using sativa. Respondents were more likely to endorse wanting to use indica if they were going to sleep soon but more likely to use sativa at a party. Hypothetical purchasing patterns (i.e., grams of cannabis purchased as a function of escalating price) did not differ between indica and sativa, suggesting that demand was similar. Taken together, cannabis users retrospectively report feeling different effects from indica and sativa; however, demand generally did not differ between cannabis subtypes, suggesting situational factors could influence whether someone uses indica or sativa. Placebo-controlled, blinded studies are needed to characterize the pharmacodynamics and chemical composition of indica and sativa cannabis and to determine whether user expectancies contribute to differences in perceived indica/sativa effects. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
市售的大麻产品通常基于所谓的植物品种（例如“ indica”或“ sativa”）进行营销。大麻行业经常声称 indica 与 sativa 大麻会引起独特的效果，并且/或者对不同的治疗适应症有用。很少有研究评估过 indica 与 sativa 的使用模式，信念，主观体验以及个人使用 indica 与 sativa 的情况。通过亚马逊 Mechanical Turk（mTurk）对大麻使用者的便利样本（= 179）进行了调查。要求参与者询问他们以前使用过的 indica 与 sativa 大麻的主观体验和意见，并完成两种大麻亚型的假设购买任务。参与者报告说，他们更喜欢在晚上使用 indica，在早晨和下午使用 sativa。参与者在使用 indica 后更有可能感到“困倦/疲倦”或“放松”，而在使用 sativa 后更有可能感到“机敏”，“充满活力”和“有动力”。如果参与者很快要入睡，则更有可能选择 indica，而在参加聚会时，则更有可能选择 sativa。假设的购买模式（即，随着价格的上涨而购买的大麻克数）在 indica 和 sativa 之间没有差异，这表明需求相似。总的来说，大麻使用者会回顾使用 indica 和 sativa 的不同感觉；但是，大麻亚型之间的需求通常没有差异，这表明情境因素可能会影响某人使用 indica 还是 sativa。需要进行安慰剂对照，盲法研究，以描述 indica 和 sativa 大麻的药效动力学和化学成分，并确定使用者的期望是否会导致对 indica/sativa 效果的感知差异。（PsycInfo数据库记录（c）2022 APA，保留所有权利）。
