Center for Alcohol and Addiction Studies, Brown University School of Public Health, Box G-S121-5, Providence, RI 02912, USA.
Center for Alcohol and Addiction Studies, Brown University School of Public Health, Box G-S121-5, Providence, RI 02912, USA.
Drug Alcohol Depend. 2024 Sep 1;262:111396. doi: 10.1016/j.drugalcdep.2024.111396. Epub 2024 Jul 11.
Cannabis demand (i.e., relative value) is usually assessed as a trait-level risk-factor for cannabis use and consequences. This study examined within-person variability in day-level intensity (i.e., amount consumed at zero cost) and O (i.e., maximum cannabis expenditure) and tested hypotheses that demand would be positively associated with day-level cannabis use.
Young adults (n=85) reporting past-month simultaneous alcohol and cannabis use completed two daily surveys for 30 days. Morning surveys assessed prior-day cannabis use and evening surveys assessed day-level demand (i.e., intensity, O). Multilevel models tested day-level effects of intensity and O on any cannabis use and flower use frequency and quantity (i.e., grams).
Approximately 52 % and 46 % of variability in intensity and O, respectively, was due to within-person change. At the day-level, higher intensity and O were associated with higher likelihood of any cannabis use, regardless of formulation; O was associated with use of flower in particular; and intensity was associated with the highest quantity of use. At the person-level, only O was associated with flower use likelihood, and only intensity was associated with flower quantity across days.
Cannabis demand demonstrated day-to-day variability, conceivably in response to various internal states and external factors. Intensity and O were related to elevated likelihood of using any cannabis, particularly flower, at the day-level. Overall, these data illustrate the validity and utility of brief cannabis demand measures, which might be used to further understand cannabis' reinforcing value at a fine-grained level.
大麻需求(即相对价值)通常被评估为大麻使用和后果的特质风险因素。本研究考察了个体日间吸食强度(即零成本吸食量)和 O(即最大大麻支出)的日内变化,并检验了需求与日间大麻使用呈正相关的假设。
报告过去一个月同时使用酒精和大麻的年轻人(n=85)完成了 30 天的两次每日调查。早上的调查评估了前一天的大麻使用情况,晚上的调查评估了当天的需求(即强度、O)。多层次模型检验了强度和 O 对任何大麻使用以及花使用频率和数量(即克)的日变化影响。
强度和 O 的个体内变化分别约占其变异的 52%和 46%。在日间水平上,较高的强度和 O 与更高的任何大麻使用可能性相关,无论剂型如何;O 与花的使用尤其相关;而强度与使用量的最高值相关。在个体水平上,只有 O 与花的使用可能性相关,只有强度与花的使用量在各天之间相关。
大麻需求表现出日变化,可能是对各种内部状态和外部因素的反应。强度和 O 与在日间水平上使用任何大麻,特别是花的可能性增加有关。总的来说,这些数据说明了简短的大麻需求测量的有效性和实用性,这些测量可以用来更深入地了解大麻在精细层面上的强化价值。