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局部蜂蜜与聚维酮碘敷料在伤口愈合方面的比较:系统评价和荟萃分析。

Comparison of topical honey and povidone iodine-based dressings for wound healing: a systematic review and meta-analysis.

机构信息

Wound Treatment Center, Tianjin Fifth Central Hospital, Tianjin 300450, P. R. China.

Department of General Surgery, Tianjin Fifth Central Hospital, Tianjin 300450, P. R. China.

出版信息

J Wound Care. 2021 Apr 1;30(Sup4):S28-S36. doi: 10.12968/jowc.2021.30.Sup4.S28.

DOI:10.12968/jowc.2021.30.Sup4.S28
PMID:33856925
Abstract

OBJECTIVES

In this review and meta-analysis, we analyse the evidence to compare the efficacy of honey and povidone iodine-based dressings on the outcome of wound healing.

METHOD

A systematic literature search was performed using PRISMA guidelines in academic databases including MEDLINE, Scopus, Embase and CENTRAL. A meta-analysis was carried out to assess the effect of honey and povidone iodine-based dressings on mean healing duration, mean hospital stay duration and visual analogue scale (VAS) score of pain.

RESULTS

From the search, 12 manuscripts with a total of 1236 participants (mean age: 40.7±11.7 years) were included. The honey-based dressings demonstrated a medium-to-large effect in reduction of mean healing duration (Hedge's g: -0.81), length of hospital stay (-3.1) and VAS score (-1.2) as compared with the povidone iodine-based dressings. We present evidence (level 1b) in favour of using honey for improvement of wound recovery as compared with povidone iodine.

CONCLUSION

This review and meta-analysis demonstrate beneficial effects of honey-based dressings over povidone iodine-based dressings for wound recovery.

摘要

目的

在本次综述和荟萃分析中,我们分析了比较蜂蜜和聚维酮碘敷料在伤口愈合结果方面疗效的证据。

方法

我们按照 PRISMA 指南,在 MEDLINE、Scopus、Embase 和 CENTRAL 等学术数据库中进行了系统文献检索。我们进行了荟萃分析,以评估蜂蜜和聚维酮碘敷料对平均愈合时间、平均住院时间和疼痛视觉模拟量表(VAS)评分的影响。

结果

通过检索,共纳入 12 篇文献,总计 1236 名参与者(平均年龄:40.7±11.7 岁)。与聚维酮碘敷料相比,蜂蜜敷料在缩短平均愈合时间(Hedge's g:-0.81)、住院时间(-3.1)和 VAS 评分(-1.2)方面具有中到大的效果。我们提供了(1b 级)证据,表明与聚维酮碘相比,使用蜂蜜敷料可改善伤口恢复。

结论

本次综述和荟萃分析表明,与聚维酮碘敷料相比,蜂蜜敷料在伤口恢复方面具有有益的效果。

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Comparison of topical honey and povidone iodine-based dressings for wound healing: a systematic review and meta-analysis.局部蜂蜜与聚维酮碘敷料在伤口愈合方面的比较:系统评价和荟萃分析。
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