Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Faculty of Public Health, Mulawarman University, Samarinda, East Kalimantan, Indonesia.
Int J Food Sci Nutr. 2022 Feb;73(1):71-81. doi: 10.1080/09637486.2021.1910631. Epub 2021 Apr 15.
We evaluated the association between intake of total polyphenols, polyphenol classes and the 10 most consumed individual polyphenols with serum total antioxidant capacity (TAC) in 749 European adolescents (53% girls; 15% overweight; 12.5-17.5 years-old) from the cross-sectional HELENA study of 2006-2007. Dietary polyphenol intake was calculated from two non-consecutive 24-h recalls matched with the Phenol-Explorer database. Multilevel linear models examined the associations between dietary polyphenols and TAC. Polyphenol intake was rather low (median = 321mg/day; p25 = 158; p75 = 536) and TAC was comparable to other literature findings (median = 1.57 mmol/L; p25 = 1.45; p75 = 1.74). Total polyphenol intake, polyphenol classes and the top 10 compounds were not associated with TAC in a linear, quadratic or cubic way in partially or fully confounder-adjusted models. A direct anti-oxidative effect of dietary polyphenol intake was not observed in European adolescents. Polyphenol biomarkers and additional antioxidant measures are needed in future prospective studies to confirm these results.
我们评估了在 749 名欧洲青少年（53%为女孩；15%超重；12.5-17.5 岁）中，总多酚、多酚类和 10 种最常食用的单体多酚的摄入量与血清总抗氧化能力（TAC）之间的关联。2006-2007 年的 HELENA 研究采用了两次非连续 24 小时的回忆来计算饮食中多酚的摄入量，并与 Phenol-Explorer 数据库相匹配。多水平线性模型检查了饮食多酚与 TAC 之间的关联。多酚的摄入量相当低（中位数=321mg/天；p25=158；p75=536），TAC 与其他文献发现相当（中位数=1.57mmol/L；p25=1.45；p75=1.74）。在部分或完全调整混杂因素的模型中，总多酚摄入量、多酚类和前 10 种化合物与 TAC 之间没有线性、二次或三次关系。在欧洲青少年中，没有观察到饮食多酚摄入量具有直接的抗氧化作用。未来的前瞻性研究需要使用多酚生物标志物和其他抗氧化措施来证实这些结果。
