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儿童 COVID-19 大流行疫苗接种。

Pediatric Vaccination During the COVID-19 Pandemic.

机构信息

Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California

Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California.

出版信息

Pediatrics. 2021 Jul;148(1). doi: 10.1542/peds.2020-047092. Epub 2021 Apr 15.

Abstract

OBJECTIVES

The impact of the coronavirus disease 2019 pandemic on vaccination coverage, critical to preventing vaccine-preventable diseases, has not been assessed during the reopening period.

METHODS

Vaccine uptake and vaccination coverage for recommended vaccines and for measles-containing vaccines at milestone ages were assessed in a large cohort of children aged 0 to 18 years in Southern California during January to August 2020 and were compared with those in the same period in 2019. Differences in vaccine uptake and vaccination coverage (recommended vaccines and measles-containing vaccines) in prepandemic (January to March), stay-at-home (April to May), and reopening (June to August) periods in 2020 and 2019 were compared.

RESULTS

Total and measles-containing vaccine uptake declined markedly in all children during the pandemic period in 2020 compared with 2019, but recovered in children aged 0 to 23 months. Among children aged 2 to 18 years, measles-containing vaccine uptake recovered, but total vaccine uptake remained lower. Vaccination coverage (recommended and measles-containing vaccines) declined and remained reduced among most milestone age cohorts ≤24 months during the pandemic period, whereas recommended vaccination coverage in older children decreased during the reopening period in 2020 compared with 2019.

CONCLUSIONS

Pediatric vaccine uptake decreased dramatically during the pandemic, resulting in decreased vaccination coverage that persisted or worsened among several age cohorts during the reopening period. Additional strategies, including immunization tracking, reminders, and recall for needed vaccinations, particularly during virtual visits, will be required to increase vaccine uptake and vaccination coverage and reduce the risk of outbreaks of vaccine-preventable diseases.

摘要

目的

新冠疫情对疫苗接种覆盖率的影响至关重要,因为它能预防疫苗可预防的疾病,但在重新开放期间尚未对此进行评估。

方法

在加利福尼亚州南部,对 0 至 18 岁的大量儿童在 2020 年 1 月至 8 月期间的疫苗接种率和推荐疫苗及含麻疹疫苗的疫苗接种覆盖率进行了评估,并与 2019 年同期进行了比较。比较了 2020 年和 2019 年疫情前(1 月至 3 月)、居家令期间(4 月至 5 月)和重新开放期间(6 月至 8 月)的疫苗接种率和疫苗接种覆盖率(推荐疫苗和含麻疹疫苗)的差异。

结果

与 2019 年相比,2020 年所有儿童在疫情期间的总疫苗和含麻疹疫苗接种率均显著下降,但 0 至 23 个月的儿童有所恢复。在 2 至 18 岁的儿童中,含麻疹疫苗接种率有所恢复,但总疫苗接种率仍较低。在疫情期间,大多数≤24 月龄的里程碑年龄组的疫苗接种覆盖率(推荐疫苗和含麻疹疫苗)下降且持续下降,而 2020 年重新开放期间年长儿童的推荐疫苗接种覆盖率较 2019 年下降。

结论

疫情期间,儿科疫苗接种率大幅下降,导致疫苗接种覆盖率下降,在重新开放期间,几个年龄组的疫苗接种覆盖率持续下降或恶化。需要采取额外的策略,包括免疫接种跟踪、提醒和召回所需的疫苗接种,特别是在虚拟访问期间,以提高疫苗接种率和疫苗接种覆盖率,降低疫苗可预防疾病爆发的风险。

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