Centre for Epidemiology and Public Health, Federal University of Alagoas, Arapiraca, Brazil.
Graduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Brazil.
Expert Rev Vaccines. 2021 Dec;20(12):1661-1666. doi: 10.1080/14760584.2021.1990045. Epub 2021 Oct 21.
COVID-19 pandemic has disrupted health services, including vaccination demand. We describe the impact of the COVID-19 pandemic on routine pediatric vaccination in Brazil.
We conducted a retrospective analysis of all vaccine doses provided to children aged 0-6 years from January 2019 to December 2020. We obtained data stratified by age group (0 to 2 years and >2 to 6 years) and Brazilian region. Difference-in-difference (DiD) analyses were performed to compare vaccine uptake in the pre-pandemic (January-February), stay-at-home (March-June), and reopening (July-December) periods.
The number of vaccine doses administered declined in the stay-at-home period. For children aged 0 to 2 years, the highest reductions were recorded in the North (-25.3%), Northeast (-16.8%) and Central-West (-10.2%) regions. For children aged >2 to 6 years, the highest decline was observed in the North (DiD = -27.2%) and South (DiD = -14.0%) regions. The number of vaccine doses administered in the reopening period has slightly increased in all regions.
Vaccination decreased during the COVID-19 pandemic. Although the number of doses recovered in part during the reopening phase, additional strategies, such as increased public awareness and vaccination booster campaigns are required.
COVID-19 大流行扰乱了卫生服务,包括疫苗需求。我们描述了 COVID-19 大流行对巴西常规儿科疫苗接种的影响。
我们对 2019 年 1 月至 2020 年 12 月期间为 0-6 岁儿童接种的所有疫苗剂量进行了回顾性分析。我们按年龄组(0 至 2 岁和>2 至 6 岁)和巴西地区进行了分层。采用差异(DiD)分析比较了大流行前(1 月至 2 月)、居家隔离(3 月至 6 月)和重新开放(7 月至 12 月)期间的疫苗接种率。
居家隔离期间接种疫苗的人数减少。对于 0 至 2 岁的儿童,北部(-25.3%)、东北部(-16.8%)和中西部(-10.2%)地区的降幅最大。对于>2 至 6 岁的儿童,北部(DiD=-27.2%)和南部(DiD=-14.0%)地区的降幅最大。在所有地区,重新开放期间接种的疫苗数量略有增加。
COVID-19 大流行期间疫苗接种率下降。尽管在重新开放阶段部分恢复了接种数量,但仍需要采取额外的策略,例如提高公众意识和开展疫苗加强运动。