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COVID-19 大流行对巴西常规儿科疫苗接种的影响。

Effects of the COVID-19 pandemic on routine pediatric vaccination in Brazil.

机构信息

Centre for Epidemiology and Public Health, Federal University of Alagoas, Arapiraca, Brazil.

Graduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Brazil.

出版信息

Expert Rev Vaccines. 2021 Dec;20(12):1661-1666. doi: 10.1080/14760584.2021.1990045. Epub 2021 Oct 21.

Abstract

BACKGROUND

COVID-19 pandemic has disrupted health services, including vaccination demand. We describe the impact of the COVID-19 pandemic on routine pediatric vaccination in Brazil.

METHODS

We conducted a retrospective analysis of all vaccine doses provided to children aged 0-6 years from January 2019 to December 2020. We obtained data stratified by age group (0 to 2 years and >2 to 6 years) and Brazilian region. Difference-in-difference (DiD) analyses were performed to compare vaccine uptake in the pre-pandemic (January-February), stay-at-home (March-June), and reopening (July-December) periods.

RESULTS

The number of vaccine doses administered declined in the stay-at-home period. For children aged 0 to 2 years, the highest reductions were recorded in the North (-25.3%), Northeast (-16.8%) and Central-West (-10.2%) regions. For children aged >2 to 6 years, the highest decline was observed in the North (DiD = -27.2%) and South (DiD = -14.0%) regions. The number of vaccine doses administered in the reopening period has slightly increased in all regions.

CONCLUSIONS

Vaccination decreased during the COVID-19 pandemic. Although the number of doses recovered in part during the reopening phase, additional strategies, such as increased public awareness and vaccination booster campaigns are required.

摘要

背景

COVID-19 大流行扰乱了卫生服务,包括疫苗需求。我们描述了 COVID-19 大流行对巴西常规儿科疫苗接种的影响。

方法

我们对 2019 年 1 月至 2020 年 12 月期间为 0-6 岁儿童接种的所有疫苗剂量进行了回顾性分析。我们按年龄组(0 至 2 岁和>2 至 6 岁)和巴西地区进行了分层。采用差异(DiD)分析比较了大流行前(1 月至 2 月)、居家隔离(3 月至 6 月)和重新开放(7 月至 12 月)期间的疫苗接种率。

结果

居家隔离期间接种疫苗的人数减少。对于 0 至 2 岁的儿童,北部(-25.3%)、东北部(-16.8%)和中西部(-10.2%)地区的降幅最大。对于>2 至 6 岁的儿童,北部(DiD=-27.2%)和南部(DiD=-14.0%)地区的降幅最大。在所有地区,重新开放期间接种的疫苗数量略有增加。

结论

COVID-19 大流行期间疫苗接种率下降。尽管在重新开放阶段部分恢复了接种数量,但仍需要采取额外的策略,例如提高公众意识和开展疫苗加强运动。

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