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新冠疫情对儿童疫苗接种覆盖率的潜在影响:以美国含麻疹疫苗接种为例的研究

Potential impact of COVID-19 pandemic on vaccination coverage in children: A case study of measles-containing vaccine administration in the United States (US).

机构信息

Merck & Co., Inc., Kenilworth, NJ, USA.

Merck & Co., Inc., Kenilworth, NJ, USA.

出版信息

Vaccine. 2021 Feb 22;39(8):1201-1204. doi: 10.1016/j.vaccine.2020.11.074. Epub 2020 Dec 9.

Abstract

BACKGROUND

The COVID-19 pandemic and stay-at-home orders have caused an unprecedented decrease in the administration of routinely recommended vaccines. However, the impact of this decrease on overall vaccination coverage in a specific birth cohort is not known.

METHODS

We projected measles vaccination coverage for the cohort of children becoming one year old in 2020 in the United States, for different durations of stay-at-home orders, along with varying catch-up vaccination efforts.

RESULTS

A 15% sustained catch-up rate outside stay-at-home orders (compared to what would be expected via natality information) may be necessary to achieve projected vaccination coverage similar to previous years. Permanent decreases in vaccine administration could lead to projected vaccination coverage levels below 80%.

CONCLUSION

Modeling measles vaccination coverage under a range of scenarios provides useful information about the potential magnitude and impact of under-immunization. Sustained catch-up efforts are needed to assure that measles vaccination coverage remains high.

摘要

背景

COVID-19 大流行和居家令导致常规推荐疫苗的接种数量出现前所未有的下降。然而,这种下降对特定出生队列的总体疫苗接种覆盖率的影响尚不清楚。

方法

我们预测了美国 2020 年即将满一岁的儿童群体的麻疹疫苗接种覆盖率,针对不同持续时间的居家令,以及不同的补种疫苗努力。

结果

在没有居家令的情况下,持续 15%的补种率(与通过出生率信息预计的情况相比)可能是实现与前几年类似的预计疫苗接种覆盖率所必需的。疫苗接种数量的永久性下降可能导致预计的疫苗接种覆盖率低于 80%。

结论

在一系列情况下对麻疹疫苗接种覆盖率进行建模,可以提供有关免疫不足的潜在规模和影响的有用信息。需要持续进行补种工作,以确保麻疹疫苗接种覆盖率保持高位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbaa/7723783/d2126aa21a8c/gr1_lrg.jpg

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