Naghipour Mohammadreza, Joukar Farahnaz, Nikbakht Hossein-Ali, Hassanipour Soheil, Asgharnezhad Mehrnaz, Arab-Zozani Morteza, Mansour-Ghanaei Fariborz
Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
GI Cancer Screening and Prevention Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Int J Endocrinol. 2021 Mar 29;2021:8862456. doi: 10.1155/2021/8862456. eCollection 2021.
The prevalence of metabolic syndrome has increased in recent decades around the world and is currently reaching epidemic levels as it is a major public health and clinical concern. The aim of this study was to evaluate the prevalence of metabolic syndrome and its related demographic factors in a population-based study.
In this cross-sectional study, the target population consisted of 10520 individuals aged 35-70 years in Phase 1 of the Persian Guilan cohort study (Guilan site/Some'e Sara) that was conducted in 2014-2017. Demographic, anthropometric, blood pressure, and biochemical data were used in this study. The IDF definitions were used to diagnose the metabolic syndrome.
The prevalence of the syndrome according to IDF and ATP definition was 42.87% (95% CI: 41.92-41.81) and 40.68% (95% CI: 39.74-41.62), respectively. The prevalence of components for central obesity, high triglyceride, HDL cholesterol, blood glucose, and hypertension components was 75.8%, 43.1%, 40.6%, 39.2% and 37.9%, respectively. All demographic variables were related to the syndrome, and among them age, gender, and residence were identified as independent and strong predictive variables in the regression model. More than 92% of the population had at least one component of the syndrome.
The results of the study show a high prevalence of metabolic syndrome risk factors. It is essential to educate healthy lifestyle behaviors and further health education in the high-risk groups identified in this study, especially the elderly, women, and rural residents.
近几十年来，代谢综合征在全球的患病率呈上升趋势，目前已达到流行程度，成为主要的公共卫生和临床关注点。本研究旨在评估一项基于人群的研究中代谢综合征的患病率及其相关人口统计学因素。
在这项横断面研究中，目标人群包括2014 - 2017年进行的波斯吉兰队列研究（吉兰站点/索梅萨拉）第一阶段的10520名35 - 70岁个体。本研究使用了人口统计学、人体测量学、血压和生化数据。采用国际糖尿病联盟（IDF）的定义来诊断代谢综合征。
根据IDF和ATP定义，该综合征的患病率分别为42.87%（95%置信区间：41.92 - 41.81）和40.68%（95%置信区间：39.74 - 41.62）。中心性肥胖、高甘油三酯、高密度脂蛋白胆固醇、血糖和高血压各组分的患病率分别为75.8%、43.1%、40.6%、39.2%和37.9%。所有人口统计学变量均与该综合征相关，其中年龄、性别和居住地在回归模型中被确定为独立且强有力的预测变量。超过92%的人群至少有该综合征的一个组分。
研究结果表明代谢综合征危险因素的患病率很高。对本研究确定的高危人群，尤其是老年人、女性和农村居民，进行健康生活方式行为教育和进一步的健康教育至关重要。
