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脾脏硬化性血管瘤样结节性转化(SANT):急腹症的罕见病因。

Sclerosing angiomatoid nodular transformation (SANT) of the spleen: a rare cause of acute abdomen.

作者信息

Ojeda Rommel, Molina Gabriel A, Jiménez Galo E, González Hernán, Pinto Johanna C, Jiménez Andres, Leon Flor M

机构信息

Department of General Surgery, Hospital IESS Quito Sur, Quito, Ecuador.

Hospital de Especialidades Carlos Andrade Marin, Quito, Ecuador.

出版信息

J Surg Case Rep. 2021 Apr 9;2021(4):rjab126. doi: 10.1093/jscr/rjab126. eCollection 2021 Apr.

DOI:10.1093/jscr/rjab126
PMID:33859815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8034883/
Abstract

Sclerosing angiomatoid nodular transformation (SANT) of the spleen is an extremely rare benign lesion. It originates from the spleen's red pulp; however, its pathogenesis is not clearly defined. These tumors are usually asymptomatic or cause nonspecific abdominal symptoms. Most SANTs are found incidentally on radiographic examination or during surgery for an unrelated condition. The differential diagnosis from other splenic tumors or malignant lesions can be challenging due to the risk for a possible malignancy of the suspicious lesion. As more SANTs are being discovered and treated, they should always be considered in the differential. We present the case of an otherwise healthy 30-year-old female; she presented with abdominal pain and a mass in her spleen. Surgery was performed, and an SANT was discovered. The patient underwent full recovery, and on follow-up is doing well.

摘要

脾脏硬化性血管瘤样结节性转化(SANT)是一种极其罕见的良性病变。它起源于脾脏红髓;然而,其发病机制尚不清楚。这些肿瘤通常无症状或引起非特异性腹部症状。大多数SANT是在影像学检查或因无关疾病进行手术时偶然发现的。由于可疑病变可能存在恶性风险,与其他脾脏肿瘤或恶性病变进行鉴别诊断具有挑战性。随着越来越多的SANT被发现和治疗,在鉴别诊断时应始终考虑到它们。我们报告一例30岁健康女性病例;她因腹痛和脾脏肿块就诊。进行了手术,发现是SANT。患者完全康复,随访情况良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0526/8034883/a254b0937038/rjab126f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0526/8034883/87fc5c23186a/rjab126f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0526/8034883/98553537020e/rjab126f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0526/8034883/a254b0937038/rjab126f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0526/8034883/87fc5c23186a/rjab126f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0526/8034883/98553537020e/rjab126f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0526/8034883/a254b0937038/rjab126f3.jpg

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Sclerosing angiomatoid nodular transformation in the spleen: A case series study and literature review.脾脏硬化性血管瘤样结节性转化:病例系列研究及文献综述
Medicine (Baltimore). 2019 Apr;98(17):e15154. doi: 10.1097/MD.0000000000015154.
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Sclerosing Angiomatoid Nodular Transformation of the Spleen: An uncommon Cause of Abdominal Pain.
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Solid Tumors of the Spleen: Evaluation and Management.脾脏实体瘤:评估与管理
J Am Coll Surg. 2017 Jun;224(6):1104-1111. doi: 10.1016/j.jamcollsurg.2016.12.043. Epub 2017 Jan 24.
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Oncol Lett. 2016 Aug;12(2):928-932. doi: 10.3892/ol.2016.4720. Epub 2016 Jun 15.
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Diagn Pathol. 2015 Jul 11;10:95. doi: 10.1186/s13000-015-0312-2.
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