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戊型肝炎病毒重叠感染:急性乙型肝炎病毒再激活的一个未被充分认识的触发因素。

Hepatitis E Virus Superinfection: an Underrecognized Trigger of Acute Hepatitis B Virus Flare.

作者信息

Obeidat Adham E, Monti Gabriel, Sae-Ow Wichit, Shinoda Hiroko, Lim Herbert

机构信息

Internal Medicine, University of Hawaii, Honolulu, USA.

School of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, USA.

出版信息

Cureus. 2021 Mar 10;13(3):e13809. doi: 10.7759/cureus.13809.

Abstract

Hepatitis E virus (HEV) infection is a significant cause of acute hepatitis in endemic areas, such as parts of Asia, Africa, and Mexico, though HEV prevalence in the United States has been estimated between 6% and 20%. Chronic hepatitis B virus (HBV) infection affects about 1 per 1.4 million people in North America. Although well documented in Asia, HBV flare secondary to HEV superinfection is rarely reported in the United States. Here, we present a case of chronic undiagnosed HBV infection with acute flare secondary to HEV superinfection.

摘要

戊型肝炎病毒(HEV)感染是亚洲、非洲和墨西哥等地流行地区急性肝炎的重要病因,尽管据估计美国的HEV感染率在6%至20%之间。慢性乙型肝炎病毒(HBV)感染在北美每140万人中约有1人受影响。虽然在亚洲有充分记录,但在美国,HEV重叠感染继发的HBV发作很少有报道。在此,我们报告一例慢性未诊断的HBV感染病例,该病例因HEV重叠感染继发急性发作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29e4/8038892/9d00241975e4/cureus-0013-00000013809-i01.jpg

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