Obeidat Adham E, Monti Gabriel, Sae-Ow Wichit, Shinoda Hiroko, Lim Herbert
Internal Medicine, University of Hawaii, Honolulu, USA.
School of Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, USA.
Cureus. 2021 Mar 10;13(3):e13809. doi: 10.7759/cureus.13809.
Hepatitis E virus (HEV) infection is a significant cause of acute hepatitis in endemic areas, such as parts of Asia, Africa, and Mexico, though HEV prevalence in the United States has been estimated between 6% and 20%. Chronic hepatitis B virus (HBV) infection affects about 1 per 1.4 million people in North America. Although well documented in Asia, HBV flare secondary to HEV superinfection is rarely reported in the United States. Here, we present a case of chronic undiagnosed HBV infection with acute flare secondary to HEV superinfection.
戊型肝炎病毒（HEV）感染是亚洲、非洲和墨西哥等地流行地区急性肝炎的重要病因，尽管据估计美国的HEV感染率在6%至20%之间。慢性乙型肝炎病毒（HBV）感染在北美每140万人中约有1人受影响。虽然在亚洲有充分记录，但在美国，HEV重叠感染继发的HBV发作很少有报道。在此，我们报告一例慢性未诊断的HBV感染病例，该病例因HEV重叠感染继发急性发作。
