Akhter Mst Jesmin, Aziz Fahima Binthe, Hasan Md Mahmudul, Islam Rakibul, Parvez Mst Misrat Masuma, Sarkar Sumon, Meher Mirza Mienur
Department of Physiology and Pharmacology, Faculty of Veterinary and Animal Sciences, Hajee Mohammad Danesh Science and Technology University, Dinajpur, Bangladesh.
Department of Microbiology and Public Health, Faculty of Veterinary Medicine and Animal Science, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh.
J Adv Vet Anim Res. 2021 Mar 5;8(1):91-100. doi: 10.5455/javar.2021.h490. eCollection 2021 Mar.
Anticoccidial drugs may lead to the development of drug resistance and drug residues. Herbal extracts could be an attractive alternative. This research was undertaken to evaluate the anticoccidial outcome of compared with the anticoccidial drug (Toltazuril) in Sonali chickens.
A total of 80 Sonali chickens were evenly and equally allocated into four groups, namely (non-infected control), (infected control), (treated with ), and (treated with Toltrazuril). All groups were experimentally infected with oocysts of mixed spp. orally except , and the mixed spp. oocyst load (OL), body weight (BW) gain, and hematological parameters were calculated.
In the findings, the highest OL reduction rate in was 100%, while the was 83.44%. Nevertheless, BW differed significantly ( < 0.01) among the different groups, while the daily BW gain was higher in amounting to 8.10 gm. In the case of hematological parameter, total erythrocyte count (TEC), hemoglobin (Hb), packed cell volume (PCV), and erythrocyte sedimentation rate in different groups were almost the same and were also statistically insignificant ( > 0.05) barring total leukocyte count resulting as significant ( < 0.05) at day 30. Additionally, the results of Pearson's correlation in at day 30 indicated a strong significant ( < 0.01) negative correlation between OL and BW ( = -0.780) with the following regression equation: = -0.16* + 433.665. Moreover, the correlation of TEC, PCV, and Hb with OL was significantly ( < 0.01) negative, = -0.786, = -0.752 and = -0.633, where the regression equations were = -0.03* + 4.51, = -0.03* + 27.42, and = -0.04* + 11.40, respectively.
Long-term use of leaves' extracts effectively controls coccidiosis in Sonali chickens and can act as an effective growth promoter.
抗球虫药物可能会导致耐药性的产生和药物残留。草药提取物可能是一种有吸引力的替代品。本研究旨在评估[提取物名称]与抗球虫药物（托曲珠利）相比对索纳利鸡的抗球虫效果。
总共80只索纳利鸡被均匀且等分为四组，即[组1名称]（未感染对照组）、[组2名称]（感染对照组）、[组3名称]（用[提取物名称]处理）和[组4名称]（用托曲珠利处理）。除[组1名称]外，所有组均经口用混合艾美耳球虫种的卵囊进行实验性感染，并计算混合艾美耳球虫种的卵囊负荷（OL）、体重（BW）增加量和血液学参数。
在研究结果中，[组3名称]的最高OL降低率为100%，而[组4名称]为83.44%。然而，不同组之间的BW差异显著（P<0.01），而[组3名称]的每日BW增加量更高，达8.10克。在血液学参数方面，不同组的总红细胞计数（TEC）、血红蛋白（Hb）、红细胞压积（PCV）和红细胞沉降率几乎相同，且在第30天时除总白细胞计数差异显著（P<0.05）外，其他均无统计学意义（P>0.05）。此外，第30天时[组3名称]的皮尔逊相关性结果表明OL与BW之间存在强显著（P<0.01）负相关（r = -0.780），回归方程为：BW = -0.16OL + 433.665。此外，TEC、PCV和Hb与OL的相关性显著（P<0.01）为负，r分别为 -0.786、-0.752和 -0.633，回归方程分别为：TEC = -0.03OL + 4.51、PCV = -0.03OL + 27.42和Hb = -0.04OL + 11.40。
长期使用[提取物名称]叶提取物可有效控制索纳利鸡的球虫病，并可作为有效的生长促进剂。
