Centre for Public Health, Queen's University Belfast, Belfast, UK.
Centre for Population Health Sciences, Hanoi University of Public Health, Hanoi, Vietnam.
Support Care Cancer. 2021 Nov;29(11):6325-6333. doi: 10.1007/s00520-021-06210-z. Epub 2021 Apr 16.
This study examined the financial toxicity faced by breast cancer (BC) patients in Vietnam and the factors associated with the risk and degree of that toxicity.
A total of 309 BC patients/survivors completed an online survey (n=209) or a face-to-face interview (n=100) at two tertiary hospitals. Descriptive statistics and χ tests were used to identify and analyse the forms and degree of financial toxicity faced by BC patients/survivors. A Cragg hurdle model assessed variation in risk and the degree of financial toxicity due to treatment.
41% of respondents faced financial toxicity due to BC treatment costs. The mean amount of money that exceeded BC patients/survivors' ability to pay was 153 million Vietnamese Dong (VND) ($6602) and ranged from 2.42 million VND to 1358 million VND ($104-58,413). A diagnosis at stage II or III of BC was associated with 16.0 and 18.0 million VND (~$690-777) more in the degree of financial toxicity compared with patients who were diagnosed at stage 0/I, respectively. Being retired or married or having full (100%) health insurance was associated with a decrease in the degree of financial toxicity.
A significant proportion of Vietnamese BC patients/survivors face serious financial toxicity due to BC treatment costs. There is a need to consider the introduction of measures that would attenuate this hardship and promote uptake of screening for the reduction in financial toxicity as well as the health gains it may achieve through earlier detection of cancer.
本研究调查了越南乳腺癌（BC）患者所面临的财务毒性及其与该毒性风险和程度相关的因素。
共有 309 名 BC 患者/幸存者在两家三级医院完成了在线调查（n=209）或面对面访谈（n=100）。描述性统计和 χ 检验用于识别和分析 BC 患者/幸存者所面临的财务毒性的形式和程度。Cragg 障碍模型评估了因治疗而导致的财务毒性风险和程度的变化。
41%的受访者因 BC 治疗费用而面临财务毒性。超出 BC 患者/幸存者支付能力的平均金额为 1.53 亿越南盾（6602 美元），范围从 242 万越南盾到 1.358 亿越南盾（104-58413 美元）。BC 诊断为 II 期或 III 期与诊断为 0/Ⅰ期的患者相比，财务毒性程度分别增加了 1600 万越南盾（690 美元）和 1800 万越南盾（777 美元）。退休或已婚或拥有 100%健康保险与财务毒性程度的降低有关。
相当一部分越南乳腺癌患者/幸存者因 BC 治疗费用而面临严重的财务毒性。有必要考虑采取措施减轻这种困难，并促进筛查的普及，以减少财务毒性以及通过早期发现癌症可能带来的健康收益。
