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Flow cytometric DNA analysis of neuroblastoma: correlation with prognostic variables and survival of patients.

作者信息

Suzuki H, Takeuchi K

机构信息

The Second Department of Surgery, Mie University School of Medicine, Tsu, Japan.

出版信息

Jpn J Surg. 1988 Jan;18(1):116-8. doi: 10.1007/BF02470858.

DOI:10.1007/BF02470858
PMID:3386067
Abstract

The DNA ploidy of tumor tissues obtained from 41 patients with neuroblastoma, or ganglioneuroblastoma, which is the histologic variant of neuroblastoma, was determined by flow cytometry. The DNA ploidy was diploid in 7 tumors (5 neuroblastomas and 2 ganglioneuroblastomas) and aneuploid in 34 tumors (20 neuroblastomas and 14 ganglioneuroblastomas). The DNA ploidy of tumor cells did not correlate with the survival of patients and there was no correlation between the DNA ploidy of tumor cells and such prognostic variables, histology, primary site, staging of tumors and operative curability.

摘要

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本文引用的文献

1
Clinical application of flow cytometry: a review.流式细胞术的临床应用:综述
Cytometry. 1981 Jul;2(1):1-13. doi: 10.1002/cyto.990020102.
2
Cellular DNA content as a predictor of response to chemotherapy in infants with unresectable neuroblastoma.细胞DNA含量作为不可切除神经母细胞瘤婴儿化疗反应的预测指标。
N Engl J Med. 1984 Jul 26;311(4):231-5. doi: 10.1056/NEJM198407263110405.
3
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[通过脉冲细胞光度术对恶性肿瘤进行DNA测量。评估生长行为和异常程度的原理及重要性]
Dtsch Med Wochenschr. 1984 May 11;109(19):738-44. doi: 10.1055/s-2008-1069266.
4
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5
Flow cytometry in clinical cancer research.临床癌症研究中的流式细胞术。
Cancer Res. 1983 Sep;43(9):3982-97.
6
A proposed staging for children with neuroblastoma. Children's cancer study group A.一种针对神经母细胞瘤患儿的分期建议。儿童癌症研究组A。
Cancer. 1971 Feb;27(2):374-8. doi: 10.1002/1097-0142(197102)27:2<374::aid-cncr2820270221>3.0.co;2-g.
7
Application of DNA flow cytometry to paraffin-embedded archival material for the study of aneuploidy and its clinical significance.DNA流式细胞术在石蜡包埋存档材料中用于非整倍体研究及其临床意义
Cytometry. 1985 Jul;6(4):327-33. doi: 10.1002/cyto.990060409.
8
Flow cytometric DNA analysis of neuroblastoma. Correlation with histology and clinical outcome.神经母细胞瘤的流式细胞术DNA分析。与组织学及临床结果的相关性。
Cancer. 1986 Dec 1;58(11):2453-8. doi: 10.1002/1097-0142(19861201)58:11<2453::aid-cncr2820581117>3.0.co;2-i.
9
Effect of section thickness on quality of flow cytometric DNA content determinations in paraffin-embedded tissues.切片厚度对石蜡包埋组织中流式细胞术DNA含量测定质量的影响。
Cytometry. 1986 Jan;7(1):41-4. doi: 10.1002/cyto.990070106.