School of Medicine, Pennsylvania State College of Medicine, Hershey, PA17033, USA.
Touro College of Osteopathic Medicine, Middletown, NY 10940, USA.
Future Cardiol. 2022 Jan;18(1):27-34. doi: 10.2217/fca-2021-0007. Epub 2021 Apr 16.
Alcohol use disorder (AUD) is highly prevalent and can lead to many cardiovascular complications, including arrhythmias. Chronic alcohol use has a dose-dependent relationship with incidence of atrial fibrillation (AF), where higher alcohol intake (>3 drinks a day) is associated with higher risk of AF. Meanwhile, low levels of chronic alcohol intake (<1 drink a day) is not associated with increased risk of AF. Mechanistically, chronic alcohol intake alters the structural, functional and electrical integrity of the atria, predisposing to AF. Increased screening can help identify AUD patients early on and provide the opportunity to educate on chronic alcohol use related risks, such as AF. The ideal treatment to reduce risk of incident or recurrent AF in AUD populations is abstinence.
酒精使用障碍(AUD)的患病率很高,可导致许多心血管并发症,包括心律失常。慢性酒精使用与心房颤动(AF)的发生率呈剂量依赖性关系,其中较高的酒精摄入量(>3 杯/天)与 AF 的风险增加相关。而慢性低水平酒精摄入(<1 杯/天)与 AF 风险增加无关。从机制上讲,慢性酒精摄入会改变心房的结构、功能和电完整性,易患 AF。增加筛查可以帮助早期发现 AUD 患者,并提供有关慢性酒精使用相关风险(如 AF)的教育机会。减少 AUD 人群中发生或复发 AF 的理想治疗方法是戒酒。