Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA; Georgia Emerging Infections Program, Atlanta, GA, USA.
Georgia Emerging Infections Program, Atlanta, GA, USA; Atlanta VA Medical Center, Decatur, GA, USA; Foundation for Atlanta Veterans Education and Research, Decatur, GA, USA.
Anaerobe. 2021 Aug;70:102364. doi: 10.1016/j.anaerobe.2021.102364. Epub 2021 Apr 14.
Updated Clostridioides difficile infection (CDI) guidelines published in 2018 recommend vancomycin as first-line treatment. Of 833 community-onset CDI cases in metropolitan Atlanta, Georgia in 2018, over half did not receive first-line treatment, although guideline adherence increased over the year. Second-line treatment was more common in patients treated in ambulatory settings.
2018 年发布的更新版艰难梭菌感染(CDI)指南建议使用万古霉素作为一线治疗药物。在 2018 年佐治亚州亚特兰大市区的 833 例社区获得性 CDI 病例中,超过一半未接受一线治疗,尽管该年度的指南遵循率有所上升。在门诊环境中接受治疗的患者更常采用二线治疗。