Relationship between First Values of Red Cell Distribution Width, Mean Platelet Volume, Platelet Distribution Width, and Hospital Mortality in Acute Deep Venous Thrombosis.

OBJECTIVE

To determine the relationship between red cell distribution width (RDW), mean platelet volume (MPV), platelet distribution width (PDW) values and mortality in acute deep vein thrombosis (DVT).

STUDY DESIGN

Descriptive study.

PLACE AND DURATION OF STUDY

Canakkale Onsekiz Mart University Health Practice and Research Hospital, Turkey, from 2015 to 2020.

METHODOLOGY

Hospitalised cases of acute DVT were detected. Discharged patients (externe group -EG), mortal course (mortality group - MG) and control group ( healthy persons without thrombosis - CG) were formed. Statistical significance of the first values of RDW, MPV and PDW between groups was evaluated. In addition, the difference between the groups was evaluated according to the age, gender, platelet count, and level of the thrombosis (proximal, distal).

RESULTS

There was a significant increase in RDW values between CG and EG (13.63 ± 1.37 vs. 15.97 ± 3.20; p=0.012), CG and MG (13.63 ± 1.37 vs. 17.85 ± 3.73; p=0.003). There was a significant increase in PDW values between CG and MG (16.78 ± 0.41 vs. 18.05 ± 1.07; p<0.001) and between EG and MG (16.98 ± 0.51 vs. 18.05 ± 1.07; p<0.001). There was no significant difference in other variables.

CONCLUSION

The results show that increased RDW values may be associated with deep venous thrombosis; and increased PDW values may be associated with mortality. Following RDW and PDW values, which are fast, inexpensive and widely available, can be useful as an early predictor of thrombosis and poor prognosis. Key Words: Red cell distribution width, Mean platelet volume, Platelet distribution width, Deep venous thrombosis, Predictor, Mortality, Poor prognosis.