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利比亚托布鲁克首批100例新冠肺炎患者的临床特征:来自资源匮乏地区的简要报告

Clinical Characteristics of the First 100 Patients of COVID-19 in Tobruk, Libya: A Brief Report From Low-Resource Settings.

作者信息

Ismail Faisal, Farag Atiya, Haq Soghra, Kamal Mohammad A

机构信息

Clinical Laboratory Department, Faculty of Medical Technology, University of Tobruk, Tobruk, Libya.

National Centre for Disease Control, Tobruk, Libya.

出版信息

Disaster Med Public Health Prep. 2021 Apr 19:1-4. doi: 10.1017/dmp.2021.123.

Abstract

OBJECTIVE

This study aims to report the clinical features of a cohort of patients with suspected coronavirus disease (COVID-19) from Tobruk, Libya, and reflect upon the diagnosis challenge in low-resource settings.

METHODS

A descriptive report of the first 100 patients with suspected COVID-19 who have visited the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and COVID-19 screening clinic at the National Centre for Disease Control in Tobruk, Libya.

RESULTS

The most common presenting symptoms were fever (90%), cough (89%), dyspnea (85%), sore throat (79%), fatigue (78%), headache (64%), loss of smell (52%), loss of taste (53%), loss of appetite (43%), nausea and vomiting (26%), diarrhea (22%), and rhinorrhea (16%); 51% of the patients had lymphocytopenia, whereas 13% had thrombocytopenia. Bilateral infiltrates were the most common radiologic finding on chest X-ray (76%), and COVID-19 IgM and/or IgG antibodies were detected in 80% of the patients, whereas only 37% of the patients were tested positive by the reverse transcriptase polymerase chain reaction (RT-PCR).

CONCLUSIONS

The disease continued its spread across the region. Fever, cough, and dyspnea were the main symptoms; 21% of the patients did not have any chest X-ray abnormalities. Initial negative results for either antibody testing or RT-PCR-testing for COVID-19 do not rule out the infection.

摘要

目的

本研究旨在报告来自利比亚托布鲁克的一组疑似冠状病毒病(COVID-19)患者的临床特征,并思考资源匮乏地区的诊断挑战。

方法

对首批100名前往利比亚托布鲁克国家疾病控制中心严重急性呼吸综合征冠状病毒2(SARS-CoV-2)和COVID-19筛查诊所就诊的疑似COVID-19患者进行描述性报告。

结果

最常见的症状为发热(90%)、咳嗽(89%)、呼吸困难(85%)、咽痛(79%)、疲劳(78%)、头痛(64%)、嗅觉丧失(52%)、味觉丧失(53%)、食欲减退(43%)、恶心和呕吐(26%)、腹泻(22%)及流涕(16%);51%的患者有淋巴细胞减少,而13%的患者有血小板减少。双侧浸润是胸部X线最常见的影像学表现(76%),80%的患者检测到COVID-19 IgM和/或IgG抗体,而仅37%的患者通过逆转录聚合酶链反应(RT-PCR)检测呈阳性。

结论

该疾病在该地区持续传播。发热、咳嗽和呼吸困难是主要症状;21%的患者胸部X线无异常。COVID-19抗体检测或RT-PCR检测的初始阴性结果不能排除感染。

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