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Taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis.味觉丧失是 COVID-19 的一个独特症状:系统评价和荟萃分析。
Chem Senses. 2023 Jan 1;48. doi: 10.1093/chemse/bjad043.
2
Olfactory dysfunction among patients with COVID-19.新冠患者嗅觉功能障碍。
Saudi Med J. 2023 Nov;44(11):1085-1103. doi: 10.15537/smj.2023.44.11.20230264.
3
Oral health related quality of life and the prevalence of ageusia and xerostomia in active and recovered COVID-19 Patients.口腔健康相关生活质量以及活动期和恢复期 COVID-19 患者味觉丧失和口干的患病率。
PeerJ. 2023 Mar 6;11:e14860. doi: 10.7717/peerj.14860. eCollection 2023.
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Neurological complications and effects of COVID-19: Symptoms and conceivable mechanisms.新型冠状病毒肺炎的神经并发症及影响:症状与可能的机制
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BMJ Open. 2022 Jun 9;12(6):e059617. doi: 10.1136/bmjopen-2021-059617.
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Glob Health Action. 2021 Oct 26;14(sup1):1983106. doi: 10.1080/16549716.2021.1983106.
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Expert Syst Appl. 2022 Jun 1;195:116554. doi: 10.1016/j.eswa.2022.116554. Epub 2022 Feb 4.
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Prevalence of Olfactory Dysfuntion in SARS-COV-2 Positive Patients.新型冠状病毒肺炎阳性患者嗅觉功能障碍的患病率
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Taste loss as a distinct symptom of COVID-19: A systematic review and meta-analysis.味觉丧失作为新冠病毒病的一种独特症状:一项系统综述和荟萃分析。
medRxiv. 2021 Oct 9:2021.10.09.21264771. doi: 10.1101/2021.10.09.21264771.

本文引用的文献

1
Is loss of sense of smell a diagnostic marker in COVID-19: A systematic review and meta-analysis.嗅觉丧失是否为 COVID-19 的诊断标志物:系统评价和荟萃分析。
Clin Otolaryngol. 2020 Nov;45(6):914-922. doi: 10.1111/coa.13620. Epub 2020 Sep 16.
2
The role of self-reported smell and taste disorders in suspected COVID‑19.自我报告的嗅觉和味觉障碍在疑似 COVID-19 中的作用。
Eur Arch Otorhinolaryngol. 2020 Sep;277(9):2625-2630. doi: 10.1007/s00405-020-06069-6. Epub 2020 May 23.
3
Objective olfactory evaluation of self-reported loss of smell in a case series of 86 COVID-19 patients.目的:对 86 例 COVID-19 患者的嗅觉自我报告丧失病例系列进行客观嗅觉评估。
Head Neck. 2020 Jul;42(7):1583-1590. doi: 10.1002/hed.26279. Epub 2020 May 21.
4
Olfactory and gustatory function impairment in COVID-19 patients: Italian objective multicenter-study.新冠病毒患者嗅觉和味觉功能障碍:意大利多中心客观研究。
Head Neck. 2020 Jul;42(7):1560-1569. doi: 10.1002/hed.26269. Epub 2020 May 21.
5
Statistical and network analysis of 1212 COVID-19 patients in Henan, China.中国河南 1212 例 COVID-19 患者的统计和网络分析。
Int J Infect Dis. 2020 Jun;95:391-398. doi: 10.1016/j.ijid.2020.04.051. Epub 2020 Apr 24.
6
The role of self-reported olfactory and gustatory dysfunction as a screening criterion for suspected COVID-19.自我报告的嗅觉和味觉功能障碍作为疑似新型冠状病毒肺炎筛查标准的作用。
Eur Arch Otorhinolaryngol. 2020 Aug;277(8):2389-2390. doi: 10.1007/s00405-020-05999-5. Epub 2020 Apr 24.
7
Acute-onset smell and taste disorders in the context of COVID-19: a pilot multicentre polymerase chain reaction based case-control study.COVID-19 相关的急性嗅觉味觉障碍:一项基于多中心聚合酶链反应的病例对照初步研究。
Eur J Neurol. 2020 Sep;27(9):1738-1741. doi: 10.1111/ene.14273. Epub 2020 May 16.
8
Clinical Presentation of COVID-19: A Systematic Review Focusing on Upper Airway Symptoms.新型冠状病毒肺炎的临床表现:以上呼吸道症状为重点的系统评价
Ear Nose Throat J. 2020 Nov;99(9):569-576. doi: 10.1177/0145561320920762. Epub 2020 Apr 13.
9
Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China.中国武汉住院的 2019 年冠状病毒病患者的神经系统表现。
JAMA Neurol. 2020 Jun 1;77(6):683-690. doi: 10.1001/jamaneurol.2020.1127.
10
Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study.嗅觉和味觉障碍作为冠状病毒病(COVID-19)轻至中度形式的临床特征:一项多中心欧洲研究。
Eur Arch Otorhinolaryngol. 2020 Aug;277(8):2251-2261. doi: 10.1007/s00405-020-05965-1. Epub 2020 Apr 6.

味觉和嗅觉丧失是索马里新冠肺炎患者的常见临床特征:一项回顾性双中心研究

Loss of Taste and Smell are Common Clinical Characteristics of Patients with COVID-19 in Somalia: A Retrospective Double Centre Study.

作者信息

Farah Yusuf Mohamud Mohamed, Garad Mohamed Yahye, Mohamed Ali Abdiladhif, Ali Adam Bakar

机构信息

Mogadishu Somali-Turkish Training and Research Hospital, Mogadishu, Somalia.

出版信息

Infect Drug Resist. 2020 Jul 29;13:2631-2635. doi: 10.2147/IDR.S263632. eCollection 2020.

DOI:10.2147/IDR.S263632
PMID:32801800
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7406326/
Abstract

PURPOSE

The purpose of this study was to identify the common clinical presentations and the evidence on the presence of ageusia and anosmia as an emerging coronavirus disease 2019 (COVID-19) symptom to better inform in both COVID-19 patients and clinicians.

PATIENTS AND METHODS

As part of a double-institutional collaboration coordinated by doctors, this study retrospectively collected and analyzed the clinical characteristics of 60 patients with COVID-19 pneumonia between April 1 and April 20, 2020. Pregnant women and patients taking anti-cancer drugs had been excluded from the study. Data from each institution's electronic medical record had been obtained.

RESULTS

Sixty patients who had RT-PCR positive for COVID-19 were included in this study; of these patients, all of them had unknown exposure to COVID-19. The mean (SD) age was 45.7 (13.5) years, and 42 were men (70%). Of these patients, 80% had at least ageusia or anosmia. The most common symptoms at the onset of illness were cough (75%), fever (71.3%), myalgia or fatigue (53.3%), anosmia (loss of smell) (40%), ageusia (loss of taste) (28.3%), sore throat (25%), shortness of breath (16.7%), headache (16.7%), and GI symptoms (diarrhea, nausea, vomiting and loss appetite) (16.7%). A total of 68.3% of COVID-19 infected patients had reported either loss of taste or smell, and about 33.3% of them had only loss of smell, while 23.3% of them had impaired taste, and 11.7% of COVID-19 infected patients had both taste and smell loss.

CONCLUSION

During the epidemic period of SARS-CoV-2 infection, when presenting patients with ageusia and anosmia, physicians should consider COVID-19 pneumonia as a differential diagnosis to achieve early identification, avoid the delayed diagnosis, and prevention of transmission.

摘要

目的

本研究旨在确定常见的临床表现以及作为新型冠状病毒肺炎(COVID-19)一种新出现症状的嗅觉减退和味觉减退的相关证据,以便更好地为COVID-19患者和临床医生提供信息。

患者与方法

作为由医生协调的双机构合作的一部分,本研究回顾性收集并分析了2020年4月1日至4月20日期间60例COVID-19肺炎患者的临床特征。孕妇和正在服用抗癌药物的患者被排除在研究之外。已获取各机构电子病历中的数据。

结果

本研究纳入了60例COVID-19核酸检测呈阳性的患者;在这些患者中,所有人均无明确的COVID-19暴露史。平均(标准差)年龄为45.7(13.5)岁,男性42例(70%)。在这些患者中,80%至少有嗅觉减退或味觉减退。发病时最常见的症状为咳嗽(75%)、发热(71.3%)、肌痛或疲劳(53.3%)、嗅觉减退(嗅觉丧失)(40%)、味觉减退(味觉丧失)(28.3%)、咽痛(25%)、呼吸急促(16.7%)、头痛(16.7%)以及胃肠道症状(腹泻、恶心、呕吐和食欲不振)(16.7%)。共有68.3%的COVID-19感染患者报告有味觉或嗅觉丧失,其中约33.3%仅有嗅觉丧失,23.3%有味觉受损,11.7%的COVID-19感染患者味觉和嗅觉均丧失。

结论

在严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染流行期间,当患者出现味觉减退和嗅觉减退时,医生应将COVID-19肺炎作为鉴别诊断考虑,以实现早期识别,避免延迟诊断,并防止传播。