Department of Animal and Poultry Science, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon S7N 5A8 (Baker-Cook, Schwean-Lardner); Department of Small Animal Clinical Sciences (Moritz, Zwueste), Department of Veterinary Biomedical Sciences (Machin), Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon S7N 5B4.
Can Vet J. 2021 Apr;62(4):367-373.
The use of T-61 as a sole euthanasia agent for birds was investigated. Nine broiler chickens were euthanized by intravenous T-61 and assessed for insensibility [brainstem reflexes: nictitating membrane reflex (NIC), palpebral blink reflex (PAL)], brain death [isoelectric electroencephalogram activity (EEG)], cessation of audible heartbeat, and abnormal electrocardiogram. Birds were considered dead when the heart rate was less than 180 beats/minute with an isoelectric EEG. No vocalization or wing flapping occurred. Both NIC and PAL were lost 10.5 s from start of injection and audible heartbeat ceased at 24.5 s. Latency to isoelectric activity was 16.6 s. All but 1 bird died within 60 s. Rapid induction of insensibility meant birds did not experience pain and distress within 10.5 s from start of injection and birds were not conscious during cardiac and circulatory arrest. Intravenous injection of T-61 is an effective and efficient euthanasia method for birds.
研究了 T-61 作为鸟类安乐死的单一药物的用途。9 只肉鸡通过静脉注射 T-61 进行安乐死，并评估其感觉丧失[脑干反射：瞬膜反射（NIC），眨眼反射（PAL）]，脑死亡[等电脑电图活动（EEG）]，心跳停止和心电图异常。当心率低于 180 次/分钟且脑电图等电时，鸟类被认为死亡。没有发声或翅膀拍打。从注射开始 10.5 秒后，NIC 和 PAL 消失，24.5 秒后心跳停止。等电活动的潜伏期为 16.6 秒。除 1 只鸟外，所有鸟都在 60 秒内死亡。快速诱导感觉丧失意味着鸟类从注射开始后 10.5 秒内不会经历疼痛和痛苦，并且在心脏和循环停止期间鸟类没有意识。静脉注射 T-61 是一种有效且高效的鸟类安乐死方法。
