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微脉冲睫状体光凝术应用于难治性青光眼患者的联合技术:睫状体混合光凝术

Combined Technique for the Application of Micropulse Cyclophotocoagulation in Patients with Uncontrolled Glaucoma: Cyclo Mix.

作者信息

Waldo Loayza-Gamboa, Julio Herrera-Quiroz, Jennifer Chávez-Vallejos, Vanessa Valderrama-Albino, Luis Córdova-Crisanto, Rosa Alvarado-Villacorta, Alejandro Valera-Cornejo Diego

机构信息

Glaucoma Department, Peruvian National Eye Institute "Francisco Contreras Campos", Lima, Perú; Research Department, Clínica Vista, Lima, Peru; Cayetano Heredia Peruvian University, Lima, Peru.

Research Department, Clínica Vista, Lima, Peru; Cayetano Heredia Peruvian University, Lima, Peru.

出版信息

J Curr Glaucoma Pract. 2020 Sep-Dec;14(3):93-97. doi: 10.5005/jp-journals-10078-1289.

Abstract

PURPOSE

To describe the outcomes of a combined technique (Cyclo Mix) in uncontrolled glaucoma cases.

MATERIALS AND METHODS

Retrospective study. The Supra 810 nm subliminal laser (Quantel Medical, Cournon d'Auvergne, France) was used. A combined technique was performed using the subliminal mode (Subcyclo) in one hemifield (power of 2,000 mW, a duty cycle of 35%, and 80-150 seconds), and the continuous wave mode (Thermo Cyclo) on the other hemifield (power of 1,000 mW, exposure time of 2 seconds per spot). The primary endpoint was the probability of surgical failure. Mean intraocular pressure (IOP) change, best-corrected visual acuity (BCVA), number of glaucoma eye drops, and complications at 6 months postoperatively were secondary outcomes.

RESULTS

Twenty-three eyes from 13 patients were included. Mean age was 61.4 ± 16.7 (range: 18-78 years), and 69% were female, with a baseline IOP of 20.3 ± 5.9 (range: 13-38 mm Hg). The cumulative probability of failure was 18 and 22% on days 90 and 180, respectively. Mean IOP reduction was -25.6 ± 20.9% at 6 months. The number of glaucoma eye drops was reduced to 1.2 ± 1 ( = 0.0024) at 6 months. No statistically significant change in the mean BCVA compared with baseline at 6 months was found ( = 0.84), and no severe complications were reported.

CONCLUSION

Cyclo Mix seems to be a safe therapy that effectively reduces the IOP and glaucoma medications in eyes with uncontrolled open-angle glaucoma for up to 6 months.

HOW TO CITE THIS ARTICLE

Waldo L-G, Julio H-Q, Jennifer C-V, Combined Technique for the Application of Micropulse Cyclophotocoagulation in Patients with Uncontrolled Glaucoma: Cyclo Mix. J Curr Glaucoma Pract 2020;14(3):93-97.

摘要

目的

描述联合技术(Cyclo Mix)在未控制的青光眼病例中的治疗效果。

材料与方法

回顾性研究。使用Supra 810 nm阈下激光(Quantel Medical,法国奥弗涅地区库尔农)。采用联合技术,在一个半视野中使用阈下模式(Subcyclo)(功率2000 mW,占空比35%,持续80 - 150秒),在另一个半视野中使用连续波模式(Thermo Cyclo)(功率1000 mW,每点曝光时间2秒)。主要终点是手术失败的概率。平均眼压(IOP)变化、最佳矫正视力(BCVA)、青光眼滴眼液使用数量以及术后6个月的并发症为次要结局。

结果

纳入了13例患者的23只眼。平均年龄为61.4 ± 16.7岁(范围:18 - 78岁),69%为女性,基线眼压为20.3 ± 5.9(范围:13 - 38 mmHg)。在第90天和180天,失败的累积概率分别为18%和22%。6个月时平均眼压降低了 - 25.6 ± 20.9%。6个月时青光眼滴眼液使用数量减少至1.2 ± 1(P = 0.0024)。6个月时与基线相比,平均BCVA无统计学显著变化(P = 0.84),且未报告严重并发症。

结论

Cyclo Mix似乎是一种安全的治疗方法,可有效降低未控制的开角型青光眼患者的眼压并减少青光眼药物使用,长达6个月。

如何引用本文

Waldo L - G, Julio H - Q, Jennifer C - V, 联合技术在未控制的青光眼患者中应用微脉冲睫状体光凝术:Cyclo Mix。《当代青光眼实践杂志》2020;14(3):93 - 97。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3934/8028033/e25d42344df3/jocgp-14-93-g001.jpg

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