Hosseini-Asl Mohammad Kazem, Taherifard Erfan, Mousavi Mohammad Reza
Department of Internal Medicine, Gastroenterology Ward, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences, Shiraz, Iran.
Gastroenterol Hepatol Bed Bench. 2021 Winter;14(1):59-66.
The present study aims to compare the effect of a short duration postprandial walking and prokinetic medications on bloating reported by healthy individuals.
Abdominal bloating imposes significant clinical, social and economic burden on the healthcare systems; however, treatment of bloating is limited and not effective in all individuals with this symptom. Prokinetic agents are recommended in the treatment of bloating in individuals without underlying disorders traditionally.
The study participants were randomized into two groups of control and intervention. In the control group, individuals were given daily domperidone plus activated dimethicone as a prokinetic medication, while the subjects in the intervention group were asked to perform a 10-15-minutewalk after each meal. The study duration was 4 weeks, the subjects were re-visited afterwards, and their symptoms was compared before and after the study.
This study consists of 94 individuals including 24 men and 70 women with mean age of 44.47±12.25 years with 49 participants in the control group and 45 participants in the intervention group. Both prokinetic medication use and minimal exercise after meals were associated with significant improvements in the GI tract symptoms such as belching, flatus, postprandial epigastric fullness/ bloating, gas incontinency and abdominal discomfort/pain (p-value <0.001). The changes in the score of the gastrointestinal symptoms from beginning to end of study between the two arms of study were not statistically significant except for postprandial epigastric fullness/ bloating symptoms where the intervention was superior to the use of prokinetics (p-value=0.002).
This study shows that physical activity could be effective in relieving abdominal bloating symptoms. In contrast to other means of treatment proposed for abdominal bloating and its related symptoms, it needs no materials or equipment and can be easily performed by any individual.
本研究旨在比较健康个体餐后短时间步行与促动力药物对腹胀的影响。
腹胀给医疗系统带来了巨大的临床、社会和经济负担;然而,腹胀的治疗方法有限,并非对所有有此症状的个体都有效。传统上,促动力剂被推荐用于治疗无潜在疾病个体的腹胀。
研究参与者被随机分为对照组和干预组。对照组个体每天服用多潘立酮加活性二甲硅油作为促动力药物,而干预组的受试者被要求每餐饭后进行10 - 15分钟的步行。研究持续时间为4周,之后对受试者进行回访,并比较他们在研究前后的症状。
本研究包括94名个体,其中男性24名,女性70名,平均年龄为44.47±12.25岁,对照组有49名参与者,干预组有45名参与者。使用促动力药物和餐后少量运动均与胃肠道症状如嗳气、放屁、餐后上腹部饱胀/腹胀、气体失禁和腹部不适/疼痛的显著改善相关(p值<0.001)。除餐后上腹部饱胀/腹胀症状外,研究两组之间从研究开始到结束胃肠道症状评分的变化无统计学意义,在该症状上干预组优于促动力药物组(p值 = 0.002)。
本研究表明身体活动可有效缓解腹胀症状。与针对腹胀及其相关症状提出的其他治疗方法相比,它不需要材料或设备,任何个体都可轻松进行。