Card J P, Moore R Y
Medical Products Department, E.I. du Pont de Nemours and Company, Wilmington, DE 19810.
Neurosci Lett. 1988 Jun 7;88(3):241-6. doi: 10.1016/0304-3940(88)90217-0.
Electron microscopic immunocytochemical localization of neuropeptide Y (NPY) was used to examine the morphology and synaptology of afferents in the rat suprachiasmatic nucleus and periventricular hypothalamus. NPY-like immunoreactivity in both areas is restricted to axon terminals which contain lucent, pleomorphic vesicles, occasional dense core vesicles and which establish asymmetric synaptic contacts with distal dendrites and spines. The data demonstrate that NPY-containing axon terminals in these two functionally distinct systems are of identical morphology and exert their effects upon neuronal activity via classical synaptic contacts.
采用神经肽Y（NPY）的电子显微镜免疫细胞化学定位技术，研究大鼠视交叉上核和室周下丘脑传入纤维的形态和突触学。这两个区域中NPY样免疫反应性仅限于轴突终末，这些终末含有透亮的、形态多样的囊泡，偶尔还有致密核心囊泡，并与远端树突和棘形成不对称突触联系。数据表明，这两个功能不同系统中含NPY的轴突终末具有相同的形态，并通过经典突触联系对神经元活动发挥作用。
