Rizzo Stefania, De Gaspari Monica, Frescura Carla, Padalino Massimo, Thiene Gaetano, Basso Cristina
Cardiovascular Pathology, Azienda Ospedaliera, Department of Cardiac, Thoracic and Vascular Sciences, and Public Health, University of Padua, Padua, Italy.
Pediatric and Congenital Cardiac Surgery, Department of Cardiac, Thoracic and Vascular Sciences, and Public Health, University of Padua, Padua, Italy.
Front Cardiovasc Med. 2021 Mar 18;8:636589. doi: 10.3389/fcvm.2021.636589. eCollection 2021.
Congenital coronary artery anomalies (CAA) include a wide spectrum of malformations present at birth with various clinical manifestations and degrees of severity. Patients may be asymptomatic, and CAA may be an incidental finding during cardiac imaging or at autopsy. However, in other cases, ischemia-related signs and symptoms, leading to an increased risk of sudden cardiac death (SCD), often as first presentation may occur. In this chapter, we discuss the normal anatomy of the coronary arteries (CA) and the pathology of CAA at risk of SCD, including our experience with victims of SCD among the young population (age <40 years) and among athletes.
先天性冠状动脉异常(CAA)包括出生时就存在的一系列畸形,具有各种临床表现和严重程度。患者可能无症状,CAA可能在心脏成像或尸检时偶然发现。然而,在其他情况下,可能会出现与缺血相关的体征和症状,导致心脏性猝死(SCD)风险增加,且往往是首发表现。在本章中,我们将讨论冠状动脉(CA)的正常解剖结构以及有SCD风险的CAA的病理学,包括我们在年轻人群(年龄<40岁)和运动员中SCD受害者的经验。