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人类社会行为的全基因组研究及其在社会学中的应用

The Genome-Wide Study of Human Social Behavior and Its Application in Sociology.

作者信息

Tanksley Peter T, Motz Ryan T, Kail Rachel M, Barnes J C, Liu Hexuan

机构信息

School of Criminal Justice, University of Cincinnati, Cincinnati, OH, United States.

Institute for Interdisciplinary Data Science, University of Cincinnati, Cincinnati, OH, United States.

出版信息

Front Sociol. 2019 Jun 26;4:53. doi: 10.3389/fsoc.2019.00053. eCollection 2019.

Abstract

Recent years have seen a push for the integration of modern genomic methodologies with sociological inquiry. The inclusion of genomic approaches promises to help address long-standing issues in sociology (e.g., selection effects), as well as open up new avenues for future research. This article reviews the substantive findings of behavior genetic/genomic research, both from the recent past (e.g., twin/adoption studies, candidate gene studies) and from contemporary genomic analyses. The article primarily focuses on modern genomic methods available to sociologists (e.g., polygenic score analysis) and their various applications for answering sociological questions. The article concludes by considering a number of areas to which genomic researchers and sociologists should pay close attention if a consilience between genomic methods and sociological research is to be fully realized.

摘要

近年来,人们一直在推动将现代基因组方法与社会学研究相结合。纳入基因组方法有望帮助解决社会学中长期存在的问题(例如选择效应),并为未来研究开辟新途径。本文回顾了行为遗传学/基因组学研究的实质性发现,包括过去(例如双胞胎/收养研究、候选基因研究)和当代基因组分析的发现。本文主要关注社会学家可用的现代基因组方法(例如多基因评分分析)及其在回答社会学问题方面的各种应用。文章最后考虑了一些领域,如果要充分实现基因组方法与社会学研究之间的融合,基因组研究人员和社会学家应密切关注这些领域。

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