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招募痴呆症患者及其照护者参与临床试验:双员感知。

Recruiting Persons with Dementia and Caregivers in a Clinical Trial: Dyads Perceptions.

机构信息

School of Nursing, University of Pennsylvania, Philadelphia, PA, USA.

Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, USA.

出版信息

West J Nurs Res. 2022 Jun;44(6):557-566. doi: 10.1177/01939459211008563. Epub 2021 Apr 17.

DOI:10.1177/01939459211008563
PMID:33870784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8522183/
Abstract

Recruitment for dementia research is challenging and costly. Using Ajzen's Theory of Planned Behavior we explored attitudes, perceived norms, and perceived behavioral control of persons living with dementia (PLWD) and their caregivers who participated in one clinical trial to better understand factors that influence dyads' decisions to enroll. We conducted semi-structured telephone interviews with 12 PLWD and 9 caregivers and utilized directed content analysis. Categories connected with positive attitudes about study enrollment were personal desires of wanting to learn and in-person meetings with knowledgeable staff. Additionally, participants said the money always helps in terms of the financial incentive. Participants reported enrolling to support another person (perceived norm). Study requirements were thought to be easy (perceived behavioral control). Participants highlighted the importance of flexible scheduling and study tasks being completed at their home. Findings can inform future recruitment efforts and should be investigated as effective recruitment methods in other clinical trials.

摘要

招募痴呆症研究人员具有挑战性和成本高。使用 Ajzen 的计划行为理论,我们探讨了参与一项临床试验的痴呆症患者 (PLWD) 和他们的照顾者的态度、感知规范和感知行为控制,以更好地了解影响二元决策的因素参加。我们对 12 名 PLWD 和 9 名照顾者进行了半结构化电话访谈,并采用了有针对性的内容分析。与研究入组的积极态度相关的类别是个人学习的愿望和与知识渊博的工作人员进行面对面的会议。此外,参与者表示,从经济激励的角度来看,这笔钱总是有帮助的。参与者表示,他们报名是为了支持另一个人(感知规范)。研究要求被认为是简单的(感知行为控制)。参与者强调了灵活安排和在家完成研究任务的重要性。研究结果可以为未来的招募工作提供信息,并应在其他临床试验中作为有效的招募方法进行调查。

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本文引用的文献

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Ethn Dis. 2020 Nov 19;30(Suppl 2):705-708. doi: 10.18865/ed.30.S2.705. eCollection 2020.
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Framework for creating storytelling materials to promote African American/Black adult enrollment in research on Alzheimer's disease and related disorders.创建故事素材的框架,以促进非裔美国/黑人成年人参与阿尔茨海默病及相关疾病的研究。
Alzheimers Dement (N Y). 2020 Sep 11;6(1):e12076. doi: 10.1002/trc2.12076. eCollection 2020.
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Challenges to and Facilitators of Recruitment to an Alzheimer's Disease Clinical Trial: A Qualitative Interview Study.招募阿尔茨海默病临床试验参与者的挑战和促进因素:一项定性访谈研究。
J Alzheimers Dis. 2019;69(4):1067-1075. doi: 10.3233/JAD-190146.
4
Barriers and recruitment strategies for precarious status migrants in Montreal, Canada.加拿大蒙特利尔不稳定身份移民的障碍和招募策略。
BMC Med Res Methodol. 2019 Feb 26;19(1):41. doi: 10.1186/s12874-019-0683-2.
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Strategies for recruitment and retention of underrepresented populations with chronic obstructive pulmonary disease for a clinical trial.招募和保留慢性阻塞性肺疾病代表性不足人群参与临床试验的策略。
BMC Med Res Methodol. 2019 Feb 21;19(1):39. doi: 10.1186/s12874-019-0679-y.
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