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2014 年至 2018 年美国军事医疗体系中的阿片类药物处方情况:处方数量减少,药丸数量减少,治疗时间缩短。

Opioid prescribing in the U.S. Military Health System, 2014 to 2018: fewer prescriptions, fewer pills, and shorter treatment duration.

机构信息

Bone & Joint Sports Medicine Institute, Naval Medical Center Portsmouth Portsmouth, VA, United States.

Eastern Virginia Medical School, Norfolk, VA, United States.

出版信息

Pain. 2022 Jan 1;163(1):e87-e93. doi: 10.1097/j.pain.0000000000002313.

DOI:10.1097/j.pain.0000000000002313
PMID:33872234
Abstract

Prescription opioids remain an important driver of the opioid crisis in the United States. The purpose of this study was to examine recent changes in opioid prescribing patterns in the Military Health System (MHS) which is a nationwide health system service active duty military personnel and civilian beneficiaries. All patients prescribed opioid analgesics by MHS providers and filled at MHS pharmacies between 2014 and 2018 were identified. Prescriptions were converted to oral morphine equivalents (OMEs) and categorized based on prescribing specialty and formulation. Total opioid prescription counts and opioid prescription counts weighted by the annual number of outpatient encounters for each specialty were calculated, as were total OMEs and daily OMEs per prescription. A total of 3,427,308 prescriptions were included. Primary care providers and surgeons wrote 47% and 29% of opioid prescriptions, respectively. Over the study period, there was a 56% decline in annual opioid prescriptions, 25% decline in median total OMEs, and a 57% decline in opioid prescriptions per patient encounter. The proportion of prescriptions written for >90 OMEs per day declined 21%. Declines in opioid prescriptions and quantities were observed in nearly all specialties over the study period. The results of this study suggest a broad-based shift towards less opioid prescribing.

摘要

处方类阿片仍然是美国阿片类药物危机的一个重要驱动因素。本研究的目的是考察美国军人健康系统(MHS)中阿片类药物处方模式的近期变化,该系统是一个为现役军人和文职受益人提供全国范围医疗服务的健康系统。确定了在 2014 年至 2018 年间,由 MHS 提供者开具并在 MHS 药房配药的所有阿片类镇痛药处方。根据开具处方的专业和制剂将处方转换为口服吗啡等效物(OMEs)并进行分类。计算了每个专业的总阿片类药物处方数和按每年门诊就诊次数加权的阿片类药物处方数,还计算了总 OMEs 和每处方 OMEs 日剂量。共纳入 3427308 份处方。初级保健提供者和外科医生分别开具了 47%和 29%的阿片类药物处方。在研究期间,阿片类药物的年处方量下降了 56%,总 OMEs 的中位数下降了 25%,每位患者就诊的阿片类药物处方量下降了 57%。每天开具 >90 OMEs 处方的比例下降了 21%。在研究期间,几乎所有专业的阿片类药物处方和用量都有所下降。本研究结果表明,阿片类药物的开具正在广泛减少。

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引用本文的文献

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Trends in annual prescription opioid receipt among US military members in the Military Health System during 2016-2021, by service, component, and deployment history.2016年至2021年期间,美国军事健康系统中军事人员按军种、组成部分和部署历史划分的年度阿片类药物处方接收趋势。
Reg Anesth Pain Med. 2024 Feb 19. doi: 10.1136/rapm-2023-105170.
2
The Role of the Pharmacist in Combating the Opioid Crisis: An Update.药剂师在应对阿片类药物危机中的作用:最新情况
Subst Abuse Rehabil. 2022 Dec 28;13:127-138. doi: 10.2147/SAR.S351096. eCollection 2022.
3
Naloxone prescribing practices in the Military Health System before and after policy implementation.
政策实施前后军事卫生系统中纳洛酮的处方实践。
Pain Rep. 2021 Mar 14;7(2):e993. doi: 10.1097/PR9.0000000000000993. eCollection 2022 Mar-Apr.
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Change in Per Capita Opioid Prescriptions Filled at Retail Pharmacies, 2008-2009 to 2017-2018.2008 - 2009年至2017 - 2018年零售药店人均阿片类药物处方量的变化。
Ann Intern Med. 2022 Feb;175(2):299-302. doi: 10.7326/M21-3042. Epub 2021 Dec 28.