Department of Genetic, Evolution, Microbiology and Immunology, Institute of Biology, State University of Campinas, Brazil.
Infect Genet Evol. 2021 Aug;92:104867. doi: 10.1016/j.meegid.2021.104867. Epub 2021 Apr 16.
I report here the genome sequences of a Bacillus paranthracis strain isolated from book page surface. The presented data show a new study field for this species, which is frequently encountered in several environment, including soil, rhizosphere and notably human samples. I provide some insights about genomic content of Bacillus paranthracis, for example the presence of multiple antibiotic resistance genes, genes for polyhydroxybutyrate metabolism, 120 genes related to stress resistance and pathogenicity-related genes such as phospholipase C, metalloprotease and a cluster for non-hemolytic enterotoxin. In vitro tests showed that this isolate has motility, ability to produce biofilm, cytotoxic and enterotoxic ability, which makes this isolate a potential pathogen.
我在此报告一株从书页表面分离得到的巴氏炭疽芽孢杆菌菌株的基因组序列。所呈现的数据为该物种的一个新的研究领域，该物种经常在包括土壤、根际和特别是人类样本在内的多种环境中被发现。我提供了关于巴氏炭疽芽孢杆菌基因组内容的一些见解，例如存在多种抗生素耐药基因、多羟基丁酸代谢基因、120 个与应激抗性和致病性相关的基因，如磷脂酶 C、金属蛋白酶和一个非溶血性肠毒素基因簇。体外试验表明，该分离株具有运动性、生物膜形成能力、细胞毒性和肠毒性能力，这使其成为一种潜在的病原体。
