Department of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden.
Acta Paediatr. 2021 Oct;110(10):2825-2832. doi: 10.1111/apa.15881. Epub 2021 May 1.
Treatment of childhood obesity is often insufficient and may be aggravated by high co-occurrence of attention-deficit/hyperactivity disorder (ADHD). We aimed to investigate whether children with overweight or obesity normalised in weight when receiving stimulant treatment for ADHD.
Growth data of 118 children were obtained from medical records at outpatient paediatric and children's psychiatric services in the Gothenburg area, Sweden. The children were diagnosed with ADHD and were between 6 and 17 years at the start of stimulant treatment. The pre-treatment data act as an internal control where every child is their own control.
At the start of treatment, 74 children had normal weight and 44 had either overweight or obesity. During the year with stimulants, the mean (SD) body mass index (BMI) in standard deviation score (SDS) decreased significantly: -0.72 (0.66) compared with 0.17 (0.43) during the year before treatment (p < 0.01). After one year with treatment, 43% of those with overweight or obesity had reached normal weight.
Stimulant treatment for ADHD yields significant weight loss. In children with overweight or obesity and ADHD, this is an important finding showing additional benefit in terms of weight management.
儿童肥胖症的治疗往往不够充分，并且可能因注意力缺陷/多动障碍（ADHD）的高共病率而加重。我们旨在研究接受 ADHD 兴奋剂治疗的儿童体重是否正常。
从瑞典哥德堡地区的儿科和儿童精神病学门诊的病历中获得了 118 名儿童的生长数据。这些儿童被诊断患有 ADHD，在开始接受兴奋剂治疗时年龄在 6 至 17 岁之间。治疗前的数据作为内部对照，每个孩子都是自己的对照。
治疗开始时，74 名儿童体重正常，44 名儿童超重或肥胖。在接受兴奋剂治疗的一年中，体重指数（BMI）的平均值（SD）标准差评分（SDS）显著下降：-0.72（0.66）与治疗前一年的 0.17（0.43）相比（p<0.01）。治疗一年后，43%的超重或肥胖儿童体重达到正常。
ADHD 兴奋剂治疗可显著减轻体重。对于超重或肥胖和 ADHD 的儿童来说，这是一个重要的发现，表明在体重管理方面具有额外的益处。
