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波多黎各消除围生期艾滋病毒和梅毒母婴传播,并自 2007 年以来持续取得成功:科学、以妇女为中心的护理和政策的融合。

Elimination of the Perinatal Transmission of HIV and Syphilis in Puerto Rico and Sustained Success since 2007: Convergence of Science, Women-Centered Care, and Policy.

机构信息

School of Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.

Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.

出版信息

P R Health Sci J. 2021 Mar;40(1):12-18.

Abstract

OBJECTIVE

There have been significant successes in the fight against HIV/AIDS due to the access to rapid HIV testing, interventions to reduce the mother-to-child transmission (MTCT) risk, potent and effective antiviral medications, and other biomedical prevention strategies. The purpose of this work is to demonstrate that Puerto Rico eliminated Mother-to-Child Transmission of HIV (MTCT) following the 2017 World Health Organization (WHO) criteria for validating the elimination of MTCT and Syphilis.

METHODS

Existing epidemiological data from Puerto Rico was used to document the elimination of MTCT and Syphilis. Data to calculate the indicators was obtained from the various divisions of the Puerto Rico Department of Health, including vital statistics, surveillance data, and programmatic outcomes.

RESULTS

Puerto Rico eliminated MTCT and syphilis, according to the WHO indicators, earlier than other countries. We can trace the outcomes to 1994 using the incidence rate of perinatally-acquired HIV of <50/100,000; to 2007 using HIV perinatal transmission rates for non-breastfeeding countries (<2%), to 2008 using 90% of women receiving ART at delivery, and to 2005 using the incidence rate of congenital syphilis of <50/100,000.

CONCLUSION

Not only have we eliminated the MTCT of HIV and syphilis, but the efforts have been sustained since 2000. The elimination of transmission of infectious diseases requires the intersection of scientific feasibility, coordinated interventions, and political will, successfully attained in Puerto Rico.

摘要

目的

由于能够快速进行 HIV 检测、采取降低母婴传播(MTCT)风险的干预措施、使用强效且有效的抗病毒药物以及其他生物医学预防策略,艾滋病防治工作取得了重大进展。本研究旨在展示,波多黎各在 2017 年世界卫生组织(WHO)验证消除 MTCT 和梅毒的标准之后,消除了 HIV 母婴传播。

方法

使用波多黎各现有的流行病学数据来证明 MTCT 和梅毒的消除。计算指标的数据是从波多黎各卫生部的各个部门获得的,包括人口统计数据、监测数据和规划成果。

结果

根据 WHO 的指标,波多黎各比其他国家更早地消除了 MTCT 和梅毒。我们可以追溯到 1994 年,当时先天获得性 HIV 的发病率<50/100,000;2007 年,非母乳喂养国家的 HIV 围产期传播率<2%;2008 年,90%的孕妇在分娩时接受了抗逆转录病毒治疗;2005 年,先天性梅毒的发病率<50/100,000。

结论

我们不仅消除了 HIV 和梅毒的母婴传播,而且自 2000 年以来,我们一直在持续努力。传染病的传播的消除需要科学可行性、协调干预和政治意愿的交叉,这在波多黎各得以成功实现。

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